Diabetes Meds Flashcards
HbA1c Tx targets for newly diagnosed
48 mmol/mol
HbA1x Tx target for diabetics who moved beyond metformin
53 mmol/mol
a weight neutral biguanide that increases insulin sensitivity and decreases liver glucose production
metformin
a feature of metformin that makes it possible to reverse diarrhea & abdominal pain by lowering the dose
dose dependent med
does metformin typically cause hypoglycaemia
no
a very dangerous side effect of metformin
lactic acidosis
a thiazoidinedione that has the same effects as metformin
pioglitazone
notable side effects of pioglitazone (5)
- weight gain
- fluid retention
- anaemia
- HF
- bladder cancer
does pioglitazone usually cause hypoglycaemia
no
the most common sulfonylurea that stimulates insulin production from pancreas
gliclazide
weight effects of gliclazide
wight gain
can gliclazide lead to hypoglycaemia
yes
when does gliclazide increase the risk of CVD/MI
when used as monotherapy
GI hormones released by GI tract in response to large meals
incretins
main incretin is … which can be inhibited by …
- GLP1 (glucagon-like peptide-1)
- DPP-4 (dipeptidyl peptidase-4)
