TXA (Tranexamic Acid)

Question 1

What is the OB use for TXA?

Answer 1

TXA is used SPECIFICALLY to treat PPH by helping blood clot formation

Question 2

What is the administration route for TXA?

Answer 2

IV injection/IV infusion

Question 3

What is the administration frequency of TXA?

Answer 3

1g slow IV injection

or

Diluted in 50 or 100mL of IV fluid, given over 10 minutes

Question 4

What are some patient contraindications for TXA?

Answer 4

Patients with an active Thromboembolic disease. Since TXA helps prevent blood clot breakdown, it can exacerbate already formed blood clots or create new clots in patients prone to clot formation

Question 5

Why would you not want to give TXA to a patient with Renal impairments?

Answer 5

Because renal impairments would cause the TXA to stay in the patient’s body longer than intended, possibly causing further complications involving blood clotting.

Question 6

When giving TXA what are some things you should monitor for?

Answer 6

Hemodynamics and assess for thromboembolic events