Hemabate (Carboprost)

Question 1

What is the OB use for Hemabate?

Answer 1

Hemabate is used to TX postpartum Uterine Bleeding related to Uterine Atony.

Question 2

What route is Hemabate given?

Answer 2

IM injection

Question 3

What is the frequency of Hemabate administration?

Answer 3

0.25mg (250mcg) IM q15-90 minutes

Question 4

What are some adverse effects of Hemabate? Specifically, the BIG one?

Answer 4

EXPLOSIVE DIARRHEA is the big side effect of Hemabate.

Otherwise, it’s the usual:
-Fever/Chills
-Headache
-HTN
-Tachycardia

Question 5

What are patient contraindications for Hemabate?

Answer 5

Patients with Asthma should not use Hemabate

Question 6

Can patients with Cardiac issues (HTN, Pulmonary/Hepatic disease) safely take Hemabate?

Answer 6

No, patients with Cardiac disease, Pulmonary disease, Hepatic disease, and Asthma should avoid Hemabate

Question 7

What should you give to a patient who is about to take hemabate to avoid the BIG adverse effect?

Answer 7

An anti-diarrheal medication

Question 8

What should be monitored in a patient taking Hemabate?

Answer 8

Vaginal bleeding and uterine tone