Tumours

Question 1

Major criteria for changing moles

Answer 1

Change in shape/size/colour

Question 2

Minor criteria for changing moles

Answer 2

Diameter >6mm
Bleeding
Sensory change
Inflammation

Question 3

Most common type of melanoma?

Answer 3

Superficial spreading malignant melanoma

Question 4

Which type of melanoma occurs on sun damaged facial skin

Answer 4

Lentigo maligna melanoma

Question 5

Where do acral/mucosal lentiginous MM occur?

Answer 5

Palms/soles/nailbeds and mucosae

Question 6

Which type of melanoma displays a vertical growth phase from the outset?

Answer 6

Nodular melanoma

Question 7

What is the breslow thickness?

Answer 7

Measures the deepest tumour cell from the granular layer of epidermis

Question 8

Breslow thickness - confined to epidermis prognosis

Answer 8

100% 5 year survival

Question 9

Breslow thickness - <1mm prognosis

Answer 9

90% 5 year survival

Question 10

Breslow thickness >3mm 5 year survival

Answer 10

60% 5 year survival

Question 11

Which type of UV is the principle carcinogen?

Answer 11

UVB

Question 12

What is a p53 tumour mutation?

Answer 12

Loss of tumour suppressor gene

Question 13

Which subtype of cancer is more common in transplant associated sqaumous cell cancers?

Answer 13

Spindle cell subtype

Question 14

What type of surgery can you use for BCCs?

Answer 14

Mohs surgery

Standard excision

Question 15

Non-surgical treatment of BCC?

Answer 15

Imiquimod

Cryotherapy

Question 16

What is actinic keratosis?

Answer 16

Dysplastic keratinocytes

Question 17

What is Bowen’s disease?

Answer 17

Full thickness dysplasia/carcinoma in situ

basically one step up from actinic keratosis

Question 18

Where is Bowen’s disease most commonly found?

Answer 18

Most commonly found on lower legs in elderly females