Passmedicine Flashcards
Peri-orbital and nasolabial scaly rash, dandruff
Seborrhoeic dermatitis
First line treatment for seborrhoeic dermatitis
Topical ketoconazole
Worst type of melanoma
Nodular melanoma
Toxic epidermal necrolysis is a rare but important side effect of which medications?
Penicillins
Symmetrical target lesions
Erythema multiforme
Treatment for excessive sweating
Topical aluminium chloride
Botox
Drugs which can cause a lichenoid eruption
Gold
Quinidine
Thiazides
What is the Koebner phenomenon
Skin lesions which appear at the site of injury
Treatment of impetigo
Topical fusidic acid
Red or black lump, oozes or bleeds, on sun-exposed skin
Nodular melanoma
Trichophyton rubrum
Fungal nail
Treatment for fungal nail
Oral terbinafine first line
alternative = oral itraconazole
Malassezia fungus causes what skin condition?
Ptyriasis versicolour
Treatment of scabies
Permethrin
Malathion lotion
Treatment of pyoderma gangrenosum
Oral steroids
Treatment of erythrasma
Erythromycin
(erythrasma is a generally asymptomatic, flat, scaly, pink or brown rash usually found in the groin or axilla - caused by overgrowth of diptheroid Corynebacterium)
What causes dermatitis herpetiformis?
Caused by deposition of IgA in the dermis
-associated with coeliac disease
How to identify cause of contact dermatitis
Skin patch test
Treatment of erythema nodosum
Usually resolves within 6 weeks - don’t usually give active treatment
What is erythema nodosum
Inflammation of subcutaneous fat
Treatment of pityriasis versicolour
Topical ketoconazole
This rash might occur after a sore throat?
Guttate psoriasis
How long will someone be itchy with scabies for?
Normal to be itchy for up to 4-6 weeks post eradication
Where are keloid scars most likely to form?
Sternum
Side effect of topical corticosteroids (e.g. clobetasone)
May cause patchy depigmentation in patients with darker skin e.g. asians
Seborrhoeic dermatitis is more common in patients with which disease?
Parkinsons
Treatment for actinic keratoses?
Topical fluorouracil cream
Most common side effect of isotretinoin
Dry skin, eyes and lips are the most common side effects
How long does pityriasis rosea usualyl last?
Usually lasts 6-12 weeks
In pemphigus, the antibodies target which structure in the skin?
Target the desmosomes
In pemphigoid, what are the antibodies targeted against?
The basement membrane
Which medication can cause spider navii? hint you take it
Oral contraceptive pill
Presents with orange-red lesions with pinpoint redder spots on the glans and adjacent areas of skin in uncircumcised me
Zoon’s balantitis
Treatment of guttate psoriasis
Reassurance and topical treatment if lesions are symptomatic
Difference between a lipoma and a soft tissue sarcoma?
Lipoma is usually <5cm
If bigger, worry about soft tissue sarcoma
Most common viral cause of erythema multiforme?
Herpes simplex
What can erythema marginatum occur after?
Rheumatic fever
Treatment of lichen planus
Topical corticosteroid e.g. clobetesone butyrate
Herald patch
Pityriasis rosea
Strawberry tongue and facial sparing
Scarlet fever
Starting on face and spreading to body
Koplik spots
Measles
Where are venous ulcers most commonly found?
Above the medial malleolus
Treatment of pityriasis rosea?
No treatment required
verisocolour is the one you treat with ketoconazole
First line topical treatment for acne?
Topical benzoyl peroxide
Significant complication of PUVA therapy?
Squamous cell skin cancer
Pemphigus or pemphigoid spares the mouth?
Bullous pemphigoid spares the mouth (bullous pemiphigAVOID)
A 34-year-old man with a history of polyarthralgia, back pain and diarrhoea is found to have a 3 cm red lesion on his shin which is starting to ulcerate. What is the most likely diagnosis?
Patient is likely to have ulcerative colitis - association with large joint arthritis, sacroilitis and pyoderma gangrenosum
Two important causes of erythema nodosum?
Tuberculosis and sarcoidosis - DO CHEST X-RAY
Common triggers of psoriasis?
Beta blockers
Lithium
A 61-year-old man presents with pruritus. He has had recurrent episodes of painful swelling in the MTP joints and a history of peptic ulcer disease. On examination he has a ‘ruddy’ complexion
Polycythemia
A 41-year-old woman requests a repeat prescription for citalopram. She also mentions she is constantly itchy and bruises easily. On examination she has reddened palms and a distended abdomen
Liver disease
“ruddy complexion”
polycythemia
What is polycythemia associated with?
Gout
Peptic ulcer disease
Chronic kidney disease
Lethargy & pallor
Oedema & weight gain
Hypertension
Treatment of bullous pemphigoid?
Oral corticosteroids
Usually has a herald patch
Pityriasis rosea
Waterlow score
Used to identify patients at risk of pressure sores
What is onchomycosis?
Another name for fungal nail
Treatment of lichen slcerosus
Steroids e.g. clobetasone propionate
You are working in general practice and see a 24-year-old male with a likely diagnosis of pityriasis rosea. What most commonly precedes this condition?
Viral infection
A lesion that may occur in a 32-year-old man with long standing Crohns disease.
Pyoderma gangrenosum
A 72-year-old man is investigated for weight loss. On examination he is deeply jaundiced and cachectic. He also has a dark velvety lesion coating his tongue.
Acanthosis nigricans
You are working in general practice and see a 17-year-old girl with a 8-day history of a lesion on her lower torso. This is a single 3cm oval plaque, pink in colour, with a scale trailing just inside the edge of the lesion. She has then had a subsequent 2-day history of generalised, non-pruritic, rash down her torso. This rash consists of lots of fine scales patches and plaques which follow the pattern of langer’s lines. What is the most likely diagnosis?
Ptyriasis versicolour
You might see a positive Nikolsky sign in toxic epidermal necrolysis, what is this?
When the epidermis separates with mild lateral pressure
What is erythroderma
Any condition that causes the majority (>90% of the skin to become inflamed, erythematous and scaly)
-most commonly: eczema, psoriasis, T-cell lymphoma, drug reactions and blistering reactions (pemphigus and pemphigoid)
This medication can cause a photosensitive reaction
Trimethoprim
Which medication would you avoid in glandular fever?
Amoxicillin!!!
Which virus accounts for 70% of erythema multiforme cases?
Herpes simplex virus
Who is dovobet contraindicated in?
Contraindicated in patients with calcium metabolism disorders and those who have viral skin lesions/fungal/bacterial/parasitic lesions
Which virus causes molluscum contagiosum?
Pox virus
Dry, fish-like scaling particularly affecting the extremities
Ichthyosis
Name a panniculitis
Erythema nodosum - inflammation of subcutaneous fat