Lectures Flashcards
When would you take a swab from an ulcer
Only if ulcer is increasingly painful/exudate/malodour/enlarging
basically if you think it is infected
ABP >1.5
Calcified
ABPI <0.8
Arterial disease
What is autolytic removal of devitalised tissue
When you use dressings to create moist wound and hydrate necrotic tissue e.g. honey
How long should you aim to heal ulcers over?
Aim to heal over 12 weeks
What is parakeratosis
Persistence of nuclei in the keratin layer
Parakeratosis = Persistence
What is hyperkeratosis
Increased thickness of keratin layer
What is acanthosis
Increased thickness of epidermis
Ancanthickness
What is nappy rash
It is an irritant contact dermatitis to urine
What does crusting indicate in atopic eczema
Indicates staph aureus infection
Monomophic punched out lesions
Eczema herpeticum
Most important gene that causes eczema
Fillagrin
What is Ramsay hunt syndrome?
Vesicles and pain in auditory canal and throat
Facial palsy
Irritation of 8th cranial nerve (deafness, vertigo, tinnitus)
What type of vaccine is the chicken pox vaccine?
Live attenuated chicken pox
Which type of HSV can cause encephalitis/disseminated infection (particularly in neonates)
HSV2
Red top container
Viral transport medium
What is the gold top container
Antibody test
Common causes of erythema multiforme?
Herpes simplex
Mycoplasma pnueomniae
Treatment of molluscum contagiosum
usually self-limiting but take months to disappear
Can be treated with local application of liquid nitrogen
Treatment of warts
Topical salicylic acid
Which virus causes warts?
Human papilloma virus
Which HPV causes genital warts?
HPV 6 and 11
Which HPV causes cervical cancer?
HPV 16 and 18
Which HPV types most commonly cause normal warts/veruccas?
HPV types 1-4
The HPV vaccine now protects against which strains?
6, 11, 16, 18
Which viruses cause herpangina?
Coxsackie virus
Echovirus
NOT HERPES VIRUS!!!
How do you diagnose herpangina?
Swab of lesion and sample of stool for enterovirus PCR
Which viruses cause hand foot and mouth?
Enteroviruses (especially coxsackie virus)
What causes erythema infectiosum?
Parvovirus B19 (slapped cheek)
-remember you will often see an arthritis as the rash fades
How do you confirm erythema infectiosum? (slapped cheek)
Antibody testing - check for parvovirus B19 IgM
Which Ig passes through placenta?
IgG
plagenta
Firm fleshy nodule on hands of farmers
orf
How is syphillis treated?
Penicillin injection
How do you diagnose syphillis?
Diagnosis by blood test or swab of chancre for PCR
Which bacteria causes Lyme disease?
Borrelia burgdorferi
Complications of lyme disease?
Early - erythema migrans
Late - heart block, nerve palsies, arthritis
Treatment of Lyme disease?
Doxycycline or amoxicillin
Which disease is caused by Aedes aegypti?
Zika
my friend Zika went to Egypt
Complications of Zika virus?
Guillain Barre and microcephaly
What type of hypersensitivity is pemphigus/pemphigoid?
Type II
What type of hypersensitivity is type purpura/rash?
Type III
Which medications can cause drug-induec bullous pemphigoid?
ACE inhibitors
Penicillin
Furosemide
Which medication can trigger linear IgA?
Vancomycin
Tinea capitis
Scalp
Tinea barbae
Beard
Tinea corporis
Body
Tinea manum
Hand
Tinea unguium
Nails
Tinea curis
Groin
Tinea pedis
Foot (athletes foot)
Which patients need sinlge room isolation and contact precautions
Patients with group A strep
Patients with MRSA
Patients with scabies (also need to wear long-sleeved gowns i’m out)