Tumors of the Skin Flashcards
Malignant neoplasm of keratinocytes that is locally invasive and slow to metastasize and assoc. w/chronic sun exposure
SCC
Where do skin SCCs usually occur in cats?
Head
If an SCC is found on a cat’s digit, what is the next step?
Thoracic rads b/c SCC in cats may be 2* to pulmonary carcinoma
Where do skin SCCs usually occur in dogs?
Digit, trunk, limbs, scrotum
Benign tumor caused by infection of epithelial cells w/species-specific papillomaviruses
Papilloma
How is papillomavirus transmitted?
Direct and indirect contact
What is the incubation period of papillomavirus?
1-2mo
Which age of dogs are most commonly affected by papillomavirus?
Younger
How soon do most papillomas regress?
3mo
How do papillomas present?
Smooth white papules, plaques, or cauliflower lesions
What regions of the body are commonly affected by papillomas?
Nose, conjunctiva, and haired skin
What is the origin of a lipoma?
Adipocyte
Are lipomas malignant or benign?
Benign
Are lipomas more common in dogs or cats?
Dogs
Where are lipomas most often found on the body?
Thorax, abdomen, proximal limbs
What do lipomas look like?
Soft, dome-like mass, can be pedunculated
Are sebaceous gland tumors more common in dogs or cats?
Dogs
What do sebaceous gland tumors look like?
Nodular, solitary, wart-like
Malignant tumor of dermal mast cells
Mast cell tumor
What is the pathogenesis of a mast cell tumor?
P53 and c-KIT mutation
Why might an MCT dog also have a coagulopathy?
Heparin in the mast cells
Reactive hyperplasia that originates from langerhans cells
Cutaneous histiocytoma
Single well circumscribed mass on the head, pinnae, or limbs of a young dog
Cutaneous histiocytoma
How do you treat a cutaneous histiocytoma?
None - spontaneously regress in 3mo
