Ferret Neoplastic Diseases Flashcards
A ferret with bilateral alopecia, swollen vulva, and excessive mounting behavior likely have what disease?
Hyperadrenocorticism or hyperestrogenism
What kind of tumor causes hyperadrenocorticism or hyperestrogenism?
Adrenal assoc. tumor
What are clinical signs of an adrenal tumor caused by?
Hyperestrogenism
What hormone is elevated in a ferret with an adrenal tumor?
Estrogen
What is the most effective treatment for an adrenal tumor in ferrets?
Adrenalectomy
Why are adrenalectomies sometimes difficult to do in ferrets?
Proximity to vena cava
What are medical treatments for hyperestrogenism?
Lupron
What is the MoA of Lupron?
Estrogen-reducing GnRH
Why is Lysodren not recommended for ferrets?
Not safe or effective like it is in dogs
What tumor is very common in ferrets >5yo?
Insulinoma
What are the most common symptoms of an insulinoma in a ferret?
Hypoglycemia and neuro signs
What is normal glucose level for a ferret?
80-120mg/dL
What level of glucose diagnoses hypoglycemia in a ferret?
<60mg/dL
Tumor of the pancreas that is derived from beta cells
Insulinoma
Secrete unregulated amounts of insulin resulting in hypoglycemia
Insulinoma
What is the most commonly performed treatment for an insulinoma in a ferret?
Surgical removal of the affected pancreas
What is the recurrence rate of a surgically removed insulinoma?
40% within 10mo
What is the Whipple’s triad of diagnostics for a ferret insulinoma?
Low fasting glucose, neuro signs, relief of symptoms w/feeding or glucose treatment
What are the two forms of ferret lymphoma?
Juvenile and adult lymphosarcoma
What is the age cut off for juvenile ferret lymphosarcoma?
<2yo
Fast-growing, aggressive lymphoblastic disease of ferrets
Juvenile lymphosarcoma
Slow-growing, chronic lymphocytic disease of ferrets
Adult lymphosarcoma
What type of MCT is most common in a ferret?
Cutaneous
What are clinical signs that may accompany a cutaneous MCT in a ferret?
Pruritus and self-excoriation
