Tumor Markers CC Lec Flashcards by Ellyza Msc

Q

TM: Prostate-Specific Antigen

A

CA: Prostate CA

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Q

TM: LD

A

CA: Hematologic Malignancies

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Q

Liver: Metastatic Bone CA & Hepatocellular CA

A

TM: ALP

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Q

Bone: Osteocarcoma

A

TM: ALP

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Q

TM: Neuron-Specific Enolase

A

CA: Neuroendocrine Tumors

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Q

TM: Serum M-Protein

A

CA: Plasma cell dyscrasias

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Q

TM: Serum Free Light Chains

A

CA: Plasma cell dyscrasias

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Q

TM: Beta 2-Microglobulin

A

CA: Hematologic Malignancies

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Q

TM: ACTH

A

CA: Pituitary Adenoma & Ectopic ACTH

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Q

TM: AVP

A

CA: Posterior Pit. Tumor

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Q

TM: C-Peptide

A

CA: Insulin-secreting tumor

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Q

TM: Calcitonin

A

CA: Medullary Thyroid Carcinoma

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Q

TM: Chromogranin A

A

Catecholamines

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Q

CA-125

A

Ovarian cancer

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Q

CA 15-3

A

Metastatic Breast Cancer

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Q

CA 19-9

A

Pancreatic cancer
GIT cancer
Adenocarcinoma

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Q

CA 27-29

A

Metastatic Breast Carcinoma

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Q

Grain Alcohol

A

Ethanol

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Q

Diuresis & Acidosis

A

Ethanol

Q

Wood Alcohol

A

Methanol

Q

Forms formic acdi

A

Methanol

Q

Causes blindness:

A

Methanol

Q

Rubbing Alcohol

A

Isopropanyl

Q

Accumulation of acetone

A

Isopropanyl

Q

Antidote: Active Charcoal

A

Isopropanyl

Q

Found in hydraulic fluid and antifreeze substances
Sweet taste and smell

A

Ethylene Glycol

Q

Antidote: Diazepam/Valium

A

Ethanol

Q

Metabolite: Formaldehyde
Product: Formic Acid

A

Methanol

Q

Metabolite: Oxalic acid & Glycolic acid

A

Ethylene Glycol

Q

Odorless, tasteless, colorless
Major toxic effect: Hypoxia

A

Carbon Monoxide

Q

Cherry red color of face

A

Carbon Monoxide

Q

Bitter almond odor

A

Cyanide

Q

Most common configuration of pesticides:

A

Organophosphates

Q

Inhibits: acetylcholinesterase

A

Organophosphates

Q

Screening: Serum ChE

A

Pesticides

Q

Pesticides confirmatory test:

A

Erythrocytic ChE/ChE in RBCs

Q

Garlic odor and mettalic taste

A

Arsenic

Q

Inhibits: sulfhydryl enzymes

A

Arsenic

Q

Reinsch Test

A

Arsenic

Q

Best specimen: Nails and skin

A

Arsenic

Q

Electroplating and galvanizing

A

Cadmium

Q

Destroys type 1 epithelial cells in lungs

A

Cadmium

Q

Blocks:
1. Dela aminolevulinic acid synthase
2. Pyrimidine 5’ nucleotidase
3. Na-K ATPase

A

Lead

Q

Specimen: first morning urine

A

Lead

Q

Inhibits: COMT

A

Mercury