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mls 3H > Tumor Markers CC Lec > Flashcards

Tumor Markers CC Lec Flashcards

1
Q

TM: Prostate-Specific Antigen

A

CA: Prostate CA

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2
Q

TM: LD

A

CA: Hematologic Malignancies

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3
Q

Liver: Metastatic Bone CA & Hepatocellular CA

A

TM: ALP

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4
Q

Bone: Osteocarcoma

A

TM: ALP

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5
Q

TM: Neuron-Specific Enolase

A

CA: Neuroendocrine Tumors

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6
Q

TM: Serum M-Protein

A

CA: Plasma cell dyscrasias

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7
Q

TM: Serum Free Light Chains

A

CA: Plasma cell dyscrasias

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8
Q

TM: Beta 2-Microglobulin

A

CA: Hematologic Malignancies

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9
Q

TM: ACTH

A

CA: Pituitary Adenoma & Ectopic ACTH

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10
Q

TM: AVP

A

CA: Posterior Pit. Tumor

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11
Q

TM: C-Peptide

A

CA: Insulin-secreting tumor

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12
Q

TM: Calcitonin

A

CA: Medullary Thyroid Carcinoma

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13
Q

TM: Chromogranin A

A

Catecholamines

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14
Q

CA-125

A

Ovarian cancer

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15
Q

CA 15-3

A

Metastatic Breast Cancer

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16
Q

CA 19-9

A

Pancreatic cancer
GIT cancer
Adenocarcinoma

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17
Q

CA 27-29

A

Metastatic Breast Carcinoma

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18
Q

Grain Alcohol

A

Ethanol

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19
Q

Diuresis & Acidosis

A

Ethanol

20
Q

Wood Alcohol

A

Methanol

21
Q

Forms formic acdi

A

Methanol

22
Q

Causes blindness:

A

Methanol

23
Q

Rubbing Alcohol

A

Isopropanyl

24
Q

Accumulation of acetone

A

Isopropanyl

25
Q

Antidote: Active Charcoal

A

Isopropanyl

26
Q
  1. Found in hydraulic fluid and antifreeze substances
  2. Sweet taste and smell
A

Ethylene Glycol

27
Q

Antidote: Diazepam/Valium

A

Ethanol

28
Q

Metabolite: Formaldehyde
Product: Formic Acid

A

Methanol

29
Q

Metabolite: Oxalic acid & Glycolic acid

A

Ethylene Glycol

30
Q

Odorless, tasteless, colorless
Major toxic effect: Hypoxia

A

Carbon Monoxide

31
Q

Cherry red color of face

A

Carbon Monoxide

32
Q

Bitter almond odor

A

Cyanide

33
Q

Most common configuration of pesticides:

A

Organophosphates

34
Q

Inhibits: acetylcholinesterase

A

Organophosphates

35
Q

Screening: Serum ChE

A

Pesticides

36
Q

Pesticides confirmatory test:

A

Erythrocytic ChE/ChE in RBCs

37
Q

Garlic odor and mettalic taste

A

Arsenic

38
Q

Inhibits: sulfhydryl enzymes

A

Arsenic

39
Q

Reinsch Test

A

Arsenic

40
Q

Best specimen: Nails and skin

A

Arsenic

41
Q

Electroplating and galvanizing

A

Cadmium

42
Q

Destroys type 1 epithelial cells in lungs

A

Cadmium

43
Q

Blocks:
1. Dela aminolevulinic acid synthase
2. Pyrimidine 5’ nucleotidase
3. Na-K ATPase

A

Lead

44
Q

Specimen: first morning urine

A

Lead

45
Q

Inhibits: COMT

A

Mercury

mls 3H (12 decks)

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