Tumor markers Flashcards
0
Q
Prostatic acid phosphatase
A
Prostate carcinoma
1
Q
PSA
A
Prostate specific antigen
- used to follow prostate carcinoma
- elevated in BPH and prostatitis
2
Q
CEA
A
CarcinoEmbryonic Antigen
- colorectal and pancreatic cancers
- gastric, breast, medullary thyroid carcinomas
3
Q
a-fetoprotein
A
Normally made by fetus (elevated in multiples gestation, neural tube defects, abdominal wall defects; decreased in Down syndrome)
-HCC, nonseminomatous germ cell rumors (testis, ovary)
4
Q
b-HCG
A
Hydatidiform moles and choriocarcinomas (gestational trophoblastic disease)
5
Q
CA-125
A
Ovarian cancer
6
Q
S-100
A
Seen in neural crest cells
-melanoma, neural tumors, schwannomas
7
Q
Alkaline phosphatase
A
Metastasis to bone, liver, Paget’s disease of bone
8
Q
Bombesin
A
Neuroblastoma, lung and gastric cancer
9
Q
TRAP
A
Tartrate-Resistant Acid Phosphatase
–Hairy cell leukemia–a B cell neoplasm
10
Q
CA-19-9
A
Pancreatic adenocarcinoma
11
Q
Calcitonin
A
Medullary thyroid carcinoma (MEN2a and 2b)
