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STEP 1 > Tumor Markers > Flashcards

Tumor Markers Flashcards

0
Q

Alpha-fetoprotein

A

Normally made by fetus, can indicate Hepatocellular carcinoma, hepatoblastoma, yolk sac (endodermal sinus) tumor, testicular cancer, mixed germ cell tumor (co-secreted with beta-hcg)

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1
Q

Alkaline Phosphatase

A

Metastases to bone, liver, Paget disease of bone, seminoma (placental ALP)

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2
Q

Beta-hCG

A

Hydatidiform moles and choriocarcinoma, testicular cancer

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3
Q

CA-15-3/CA-27-29

A

Breast cancer

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4
Q

CA-19-9

A

Pancreatic adenocarcinoma

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5
Q

CA-125

A

Ovarian cancer

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6
Q

Calcitonin

A

Medullary thyroid cancer

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7
Q

CEA

A

Recurrence of colorectal and pancreatic, also but lesser degree: gastric, breast, and medullary thyroid

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8
Q

PSA

A

Prostate-specific antigen: prostate adenocarcinoma, BPH, and prostitis (questionable use as non-specific)

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9
Q

S-100

A

Neural crest origin: melanoma, neural tumor, schwannomas, langerhans cell histiocytosis

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10
Q

TRAP - Tartrate-resistant Acid Phosphatase

A

Hairy cell leukemia

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STEP 1 (22 decks)

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