Carcinogens Flashcards
Alkylating Agents
Organ: Blood - Leukemia/lymphoma
Source: side effect of chemotherapy
Aflatoxins
Organ: Liver - hepatic ellipse carcinoma
Source: Aspergillus
Aromatic Amines (e.g. Benzidine, 2-naphthyline)
Organ: bladder - transitional cell carcinoma
Source:
Alcohol/Ethanol
Organ: esophagus - squamous cell carcinoma; Liver - Hepatocellular carcinoma; pancreas - pancreatic carcinoma
Source: drinking
Arsenic
Organ: Liver - Angiosarcoma; Lung - Lung cancer; Skin - squamous cell carcinoma of the skin (lightens skin)
Source: Arsenic is present in cigarette smoke
Asbestos
Organ: Lung - Broncogenic Carcinoma > Mesothelioma
Source: fireproofing, steal in cement
Cigarette smoke
Organ: bladder - transitional cell carcinoma; cervix - cervical carcinoma; esophagus - squamous cell/adenocarcinoma; Kidney - Renal cell carcinoma; Larynx - squamous cell carcinoma; Lung - squamous cell carcinoma and small cell; Pancreas - pancreatic adenocarcinoma
Source: smoking
Carbon Tetrachloride
Organ: Liver - centrilobular necrosis and fatty change
Source:
Ionizing radiation
Organ: Thyroid - papillary thyroid cancer; lymph - AML, CML (free radicals)
Source: radiation therapy
Radon
Organ: Lung - lung cancer ( 2nd leading cause)
Source: natural gas
Nitrosamines
Organ: Stomach - Gastric cancer
Source: smoked foods ( ESP japan)
Napthylamine
Organ: bladder - urothelial carcinoma
Source: cigarette smoke
Vynile Chloride
Organ: Liver - Angiosarcoma
Source: PVC pipes, occupational exposure
Nickel, Chromium, Beryllium, or Silica
Organ: lung - lung cancer
Source: occupational exposure (electronics, NASA)
Nonionizing radiation (UVB)
Organ: Skin - basal cell carcinoma, squamous cell carcinoma, melanoma
Source: sun exposure leads to formation of pyrimidine dimers in DNA
