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MTAP 2 - HISTO FINALS > Tumor Markers > Flashcards

Tumor Markers Flashcards

1
Q

T/ F. IHC detects stages of cancer

A

True

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2
Q

Tumor markers are found in

A

Tissues

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3
Q

Marker for Epithelial Tissue cells

A

Keratin

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4
Q

Marker for Epithelial Tissue cells; used as diagnosis marker for CARCINOMA

A

Keratin

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5
Q

Epithelial Tumor Marker for LUNGS, OVARY, UTERUS cancer

A

CK 7

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6
Q

Epithelial Tumor Marker for Stomach and COLON

A

CK 20

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7
Q

T/F. All carcinoma are tested positive for CK

A

FALSE

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8
Q

An epithelial tissue marker that is useful for detecting SITE of tumor

A

Epithelial Membrane Antigen

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9
Q

Epithelial Tissue Marker; used for diagnosis of ADENOCARCINOMA + BLK (Breast, Lung, Kidney)

A

Epithelial Membrane Antigen

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10
Q

An oncofetal antigen

A

Carcinoembryonic Antigen (CEA)

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11
Q

Differentiates Adenocarcinoma from mesothelioma

A

Carcinoembryonic Antigen (CEA)

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12
Q

Cancers in the ______ is associated with CEA

A

CCBP

Colon
Cervix
Breast
Pancreas

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13
Q

Cancer of epithelial tissue and glands

A

Adenocarcinoma

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14
Q

Differentiates LUNG ADENOCARCINOMA and MESOTHELIOMA

A

Thyroid Transcription Factor - 1 (TTF-1)

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15
Q

Found in all thyroid neoplasm

A

TTF-1

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16
Q

Tumor marker for GIT cancer

A

CEA

17
Q

Highly Specific antigen for prostate

A

Prostate Specific Antigen

18
Q

Tumor marker for Prostate, Pancreas, and Salivary tumor

A

Prostate Specific Antigen (PSA)

19
Q

Associated with Prostate infection

A

Prostate Specific Antigen (PSA)

20
Q

Tumor marker seen in Breast Epithelial cells

A

Estrogen Progesterone Receptor

21
Q

T/F.

ER/PR is seen in MYOEPITHELIAL CELLS

A

false

22
Q

Purpose of ER/PR

A
  1. Prognosis and treatment for breast cancer
  2. Identification of Metastatic Breast Carcinoma
23
Q

Patient with Breast cancer currently under medication has a (+) ER/PR test =

A

good prognosis

24
Q

diagnosis marker for cancer of SKELETAL, CARDIAC, AND SMOOTH MUSCLE CELL

A

Actin

25
Q

Normally seen in mesenchymal cells

A

Vimentin

26
Q

Tumor marker for
1. Sarcoma
2. Melanoma
3. Leukemia
4. Seminoma
5. Schwannomas

A

Vimentin

27
Q

Highly specific for Myogenic tumor

A

Desmin

28
Q

Confirm diagnosis for ASTROCYTOMA

A

Glial Fibrillary Acidic Protein (GFAP)

29
Q

Produced by Placental Syncytiotrophoblast

A

Human Chorionic Gonadotrophin (HCG)

30
Q

Diagnostic Choriocarcinoma

A

HCG

31
Q

Best screening marker for LYMPHOMA

A

CD45

32
Q

Tumor marker for:

Embryonic Marker
Teratoma
Hepatocellular carcinoma

A

Alpha Feto Protein (AFP)

33
Q

Two most common marker for assessing proliferation of tumor

A

Ki + MIB-1

MTAP 2 - HISTO FINALS (16 decks)

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