Tumor Markers Flashcards

1
Q

T/ F. IHC detects stages of cancer

A

True

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2
Q

Tumor markers are found in

A

Tissues

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3
Q

Marker for Epithelial Tissue cells

A

Keratin

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4
Q

Marker for Epithelial Tissue cells; used as diagnosis marker for CARCINOMA

A

Keratin

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5
Q

Epithelial Tumor Marker for LUNGS, OVARY, UTERUS cancer

A

CK 7

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6
Q

Epithelial Tumor Marker for Stomach and COLON

A

CK 20

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7
Q

T/F. All carcinoma are tested positive for CK

A

FALSE

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8
Q

An epithelial tissue marker that is useful for detecting SITE of tumor

A

Epithelial Membrane Antigen

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9
Q

Epithelial Tissue Marker; used for diagnosis of ADENOCARCINOMA + BLK (Breast, Lung, Kidney)

A

Epithelial Membrane Antigen

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10
Q

An oncofetal antigen

A

Carcinoembryonic Antigen (CEA)

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11
Q

Differentiates Adenocarcinoma from mesothelioma

A

Carcinoembryonic Antigen (CEA)

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12
Q

Cancers in the ______ is associated with CEA

A

CCBP

Colon
Cervix
Breast
Pancreas

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13
Q

Cancer of epithelial tissue and glands

A

Adenocarcinoma

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14
Q

Differentiates LUNG ADENOCARCINOMA and MESOTHELIOMA

A

Thyroid Transcription Factor - 1 (TTF-1)

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15
Q

Found in all thyroid neoplasm

A

TTF-1

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16
Q

Tumor marker for GIT cancer

17
Q

Highly Specific antigen for prostate

A

Prostate Specific Antigen

18
Q

Tumor marker for Prostate, Pancreas, and Salivary tumor

A

Prostate Specific Antigen (PSA)

19
Q

Associated with Prostate infection

A

Prostate Specific Antigen (PSA)

20
Q

Tumor marker seen in Breast Epithelial cells

A

Estrogen Progesterone Receptor

21
Q

T/F.

ER/PR is seen in MYOEPITHELIAL CELLS

22
Q

Purpose of ER/PR

A
  1. Prognosis and treatment for breast cancer
  2. Identification of Metastatic Breast Carcinoma
23
Q

Patient with Breast cancer currently under medication has a (+) ER/PR test =

A

good prognosis

24
Q

diagnosis marker for cancer of SKELETAL, CARDIAC, AND SMOOTH MUSCLE CELL

25
Normally seen in mesenchymal cells
Vimentin
26
Tumor marker for 1. Sarcoma 2. Melanoma 3. Leukemia 4. Seminoma 5. Schwannomas
Vimentin
27
Highly specific for Myogenic tumor
Desmin
28
Confirm diagnosis for ASTROCYTOMA
Glial Fibrillary Acidic Protein (GFAP)
29
Produced by Placental Syncytiotrophoblast
Human Chorionic Gonadotrophin (HCG)
30
Diagnostic Choriocarcinoma
HCG
31
Best screening marker for LYMPHOMA
CD45
32
Tumor marker for: Embryonic Marker Teratoma Hepatocellular carcinoma
Alpha Feto Protein (AFP)
33
Two most common marker for assessing proliferation of tumor
Ki + MIB-1