Tubular Organs Flashcards
how tubes are formed
Sheets of tissue folding
De Novo
Diverticulae
Branching
sheets of tissue folding
- As the embryo grows, it starts bending and folding
- Tissue folding results in tubular shapes
1. Foregut
2. Endocardial tube
De Novo
- blood vessel (tube) formation
1. Vasculogenesis: vessel arising from a blood island
2. Angiogenesis: new vessels sprout from existing ones
Vasculogenesis
Mesoderm –> Hemangiobalsts –> Tube formation
Diverticulae
Glands, auditory tube, lungs, liver, pancreas
Branching
blood vessels, airways
Typical Vascular Tube layers
- Tunica Intima
- Tunica Media
- Tunica Adventitia
Tunica Intima
- Endothelium: specialized epithelium
- Basal lamina (connective tissue)
- Subendothelial connective tissue
- Internal elastic membrane (connective tissue)
Vasa Vasorum
-blood vessel that connects to the larger vessel
non-vascular tube example
esophagus
non-vascular tube structure
Tunica mucosa
Tunica Submucosa
TUnica Muscularis
Tunica Adventitia
Tunica Mucosa
Lamina epithelialis (innermost)
Lamina propria
Lamina muscularis mucosa
Tunica Submucosa
- Connective tissue
- Blood vessels and nerves
- Ganglia and plexuses
- Glands (limited)
Tunica muscularis
- Inner circular layer
- Outer longitudinal layer
- Ganglia and plexuses
Tunica Adventitia
-Connective tissue (loose or tense)
esophagus within mediastinum
- Esophagus runs in the mediastinum
- Adventitia is a loose connective tissue that is replaced by serosa once esophagus passes through the esophageal hiatus of the diaphragm
Serosa
visceral covering of an organ
Glands
Endocrine
Exocrine
Endocrine
Secreting into the blood a product that has a specific effect on a distant organ or tissue
-pituitary hormones, insulin
Exocrine
Secreting into a lumen or duct a product that has an effect at another site
-pancreatic
Layer with the most modifications
Tunica mucosa
Esophagus modifications
Esophageal glands
Stomach modifications
Gastric pits which open into gastric glands
Small intestine modifications
Intestinal villi- extension towards lumen
Intestinal crypts - endothelial cells are multiplying
Duodenal glands
Modifications of Large intestine
Intestinal crypts
-Lots of mucous production : goblet cells
Rectum/Anus Modifications
Glands and cells decrease
External openings of tubes
Mucocutaneous junctions
Evaluation of Tubular Organ
- Visual examination of openings of tubes
- Visualization of internal structures with speculum or fiberoptic scope
- Palpation (internal/external)
- Imaging
- Biopsy