Tuberculosis Flashcards
Low-grade fever, night sweats, anorexia, weight loss, chest pain, cough and hemoptysis:
Presentation
Etiology:
Mycobacterium tuberculosis
Reservoir:
Man and cattle
Transmission:
Cough, sneeze and talk
Incubation period:
6-12 months
Transmission period after starting the treatment:
Reduced transmission after 2 weeks of treatment
Complications:
Repeated resp. infections, Empyema, Bronchiectasis and Atelectasis
Diagnosis:
Acid-fast bacilli smear or culture
Collect of the Acid-fast bacilli smear:
2 collections (at the first appointment and at awakening of the next day)
TB suspect with smear(-), Extrapulmonar TB and HIV+:
Acid-fast bacilli culture indications
The most specific test for TB:
Acid-fast bacilli culture
Rx finding that Indicates advanced infection; associated with a high bacterial load:
Cavity
Rx finding that represent old infection, tuberculomas:
Homogeneously calcified nodules
At Rx - Numerous small nodular lesions that resemble millet seeds:
Miliary TB
Screening method:
PPD
Method that isnt sufficient for diagnosisÇ
PPD
Pneumonia, Lung abscess, Paracoccidioidomycosis, Histoplasmosis, Sarcoidosis and Bronchial carcinoma:
DDx
Areas with high population density, poor socioeconomic and sanitary conditions:
Regions most affected
Intensive or First Phase Treatment of all forms of TB, except meningitis:
2 months of “RIPE”
Maintenance or Second Phase Treatment of all forms of TB, except meningitis:
4 months of “RI”
Rifampicina:
150mg
Isoniazida:
75mg
Pirazinamida:
400mg
Etambutol:
275mg
Cough with expectoration lasting 3+ weeks, fever, hyporexia, weigh loss and compatible Rx:
TB suspect
Contacts control, BCG vacination and Chemoprophylaxis:
Control measures
Hematogenous spread with systemic involvement with infectious toxic framework and risk of meningitis:
Miliary TB
Indication of Acid-fast bacilli smear:
Cough lasting 3+ weeks
Bacteriological control monitoring should be preferably performed:
monthly
Bacteriological control monitoring must be performed at minimum:
At the end of the 2nd, 4th and 6th month of treatment
PPD reading:
After 48-72h of the application
Interfere with PPD results:
Disseminated TB, AIDS, Neoplasia and Corticosteroids use
Extrapulmonary TB diagnosis:
Biopsy and culture
Duration of the treatment:
6 months
20-35kg Dosage:
2cps
36-50kg Dosage:
3cps
+50kg Dosage:
4cps
If the treatment fail:
Culture, Drug sensitivity test and Refer to reference service
2 smears or 1 smear + Culture or 1 smear + Rx or Suggestive presentation + Rx + Other suggestive exams:
Diagnostic Criteria
Chemoprophylaxis:
Isoniazida por 6m