Trematodes sukka Flashcards
Typical features of Trematodes: body shape: \_\_\_\_\_\_\_\_ segmented?: \_\_\_\_\_\_\_\_ body cavity?: \_\_\_\_\_\_\_\_ GI Tract:: \_\_\_\_\_\_\_\_ Separate sexes?: \_\_\_\_\_\_\_\_ All parasitic?: \_\_\_\_\_\_\_\_
body shape: Flat/oval or leaf like segmented?: No body cavity?: No GI Tract:: Yes, no anus Separate sexes?: No except a few species All parasitic?: Yes
All flukes of domestic animals are ____
digeneans
What is characteristic about Digenea life cycles?
Require one or more IH
#1 usually a mollusk
alternate asexual and sexual stages
General characteristics of digenean trematodes: body
body is flattened dorso ventrally
non segmented
leaf like shape
vary in size
General characteristics of digenean trematodes: external covering
Tegument
Syncytium- lacks ditinct cell boundaries
metabolically active (absorption/secretion)
may contain microvilli, spines, etc
T/F trematodes are coelomate organisms
FALSE- they are acoelmate- lack body cavity/coelom
organs are suspended in paranchyma
T/F in general the body part of the trematode responsible for absorption/secretion, the tegument, is located underneath the muscle layer
FALSE, muscle layer is under the tegument, it provides sluggish locomotion
How many suckers does the typical trematode have, where are they located?
Two;
anterior= oral sucker
ventral= acetabulum
T/F in genreal the mouth opening of trematodes is located within the oral sucker
FALSE located within the anterior sucker
T/F in general tematodes do not have teeth/lips
True
What are the 3 parts of teh typical trematodes digestive tract?
muscular pharynx, esophagus, blind gut/cecum
Since they dont have a b-hole… what happens to ingested food
cecal contents are regurgitated “Fluke Puke”
What is important about the typical characteristics of the Repro tract of tematodes?
Hermaphroditic
morphology of uterus, ovaries, testis of diagnostic value
How are trematode eggs detected?
Via sedimentation
What may be added to fecal sedimentation analysis for trematodes?
methylene blue
What are the 7 stages of the general life cycle of trematodes?
Adult Egg- (developing embryo enclosed by shell, usually has operculum) Miracidium Sporocysts Rediae Cercariae Metacercariae
What is a miracidium?
ciliated free swimming larvaa; enters snail intermediate host
T/F The sporocyst stage is essential for the development of the GI tract of trematodes
FALSE it doesnt have a GI tract
T/F The rediae stage is essential for the development of the GI tract of trematodes
TRUE-ish this is the stage where the rudimentary digestive tract develops
____ is the stage at which the trematode leaves the snail
cercadiae
____ is the stage w/in the 2nd IH or encysted on vegetation
metacercariae
____ is the infective stage of the trematode life cycle
metacercariae
How do companion animals typically acwuire Digenea trematodes?
acquired by eating fish, reptiles, amphibians, crustacians
What are the common digenea worms we learned for companion animals and the species they infect?
Nanophyteus salmincola (dog) Platynosomum fastosum (cat) Alaria spp (Dog/cat) Paragonimus kellicotti (Dog)
How do RMTs typically acquire digenea trematodes?
acquired by eating metacercariae on vegetatiojn or ants
What are the common digenea worms we learned for RMTs and the species they infect?
Fasciola hepatica (Cattle>sm RMT)
Fascioloides magna (Deer, domestic RMT accidental)
Dicrocoelium dendriticum (Sheep>dom RMT, cervids)
Paramphistomum (Cattle>sm RMT)
Cotylophorum (sm RMT>Cattle)
What digenean trematode is known for infecting ants?
Dicrocoelium
this fluke’s real significance is that it is a vector for 2 rickettsial diseases
Nanophyetus salmoncida
What are the definitive and IH of N. salmoncida?
DH fish eating mammals, primarily raccons and spotted skunk, canines
IH 1 is snails that inhabit fresh/brackish water on coasts of WA, OR, CA
IH2 salmonid fishes
Why do we only see infections of Nanophyetus salmoncida in Pacific Northwest?
Only place that has BOTH intermediate hosts available
snail distribution is the major factor
outline the life cycle of Nanophyetus salmoncida
Adults pass eggs in feces
Miracidium develp in egg in environment in 3 mo
Miracidium hatches, penetrates snail, undergoes asexual reprod -> cercaia
Cercaira exit snail, penetrate fish, encyst as metacercaria in tissues
DH eats metacercaria in fish; can live 5 years, infective for several mo at low temp
Metacercariae excyst from fish tissue in DH attach to SI mucosa and mature to adults
What are the typical ckinical signs of N. salmoncida infection?
can cause superficial enteritis and possibly a hemorrhagic enteritis
What are the 2 rickettsial diseases associated with Nanophyetus salmoncida? which is more deadly?
“Salmon poisoning”- more deadly
Elokomin fluke fever
What is salmon poisoning/clin signs?
Neorickettsia helminthoeca
ONLY IN CANIDS
sudden onset, incubation 5-7
anorexia/high fever
purulent ocular discharge
vomiting, profuse, +/- hemorrhagic diarrhea
enlarged lymphnodes
What is the prognosis of “salmonoid poisoning”
60-90% mortality if untreated in 5-7 days
survivors immune
What causes Elokomin fluke fever, what are the clinical signs of it?
another strain Neorickettsia hemlinthoeca
clinical signs occur in a broader host range (not canids), high morbity, low mortality
signs similar to salmoidm but not as severe
What are the diagnosis and treatment of the rickettsial diseases?
Diagnosis:
fluke eggs in feces supportative evidence
detect rickettsia in lymph node aspirate
Tx
for both:
oxytetracyline IV
other tetracyclines, sulphonamides, penicillins
What species are infected with Alaria spp?
Several canids, felids, and mink
What are the IH hosts of Alaria?
1 is snail
2 is frog or toad
paratenic hosts- frogs, rodents, snakes etc
Where do cycles of Alaria primarily occur?
primarily in northern half of US
can occur in dogs/cats allowed to roam
Describe the adult Alaria
small flukes ~2-6mm long
anterior portion of body expanded and flattened
posterior body is rounded
Is there anything special about Alaria eggs?
meh i guess the very faint suture line for the operculum?
Alarie life cycle… GO!
DH ingests paratenic or IH2
mesocercaria released from muscles, migrate to lungs become metacercaria
migrates via blodd, or body cavities to lungs
coughed up/swallowed
develop to adults in SI
Clinical signs associated w/ Alaria
usually asymptomatic
heavy infection- duodentitis
wandering worms- associated pathology
adults are short lived
What happens if a human is an accidental host how deos it happen?
Fatalities associated w/ eating frog legs
ingest mesocercaria in PH of 2nd IH
___ this fluke is associated w/ crayfish
Paragonimus kellicoti
What are the hosts of Paragonimus kellicoti?
natural DH: mink, muskrat,
IH1 aquatic or amphibious snails
IH2 fresh water crayfish
How is DH infected with Paragonimus kellicoti?
Eats crayfish containing metacercaria
What do teh adult Paragonimus look like?
kinda like Mr potatoehead…
1.2 to 3/4 inch ling, ovoid, fleshy
reddish grey to mottled when fresh
SPINES ON THE TEGUMENT
What is teh key characterisitc of P.. kellicoti eggs?
distinctive operculum with thickened collar at suture line
What is Paragonimus life cycel in the DH?
Metacercariae excyst in gut
enter peritoneal cavity
migrate through diaphragm to lungs
penetreate lungs
mature to adults in cycsts (2 flukes/cyst
cyst comm w/ bronchioles
eggs coughed up, swallowed passed in feces
What are the clinical signs of P. kellicoti?
respiratory signs lethargy intermittent cough rusty colored sputum death if infection severe cysts develop in other organs
What is the pathology associated w/ larval migration of P. kellicoti?
eosinophilic peritonities, pleuritis, myositis
multifocal pleural hemorrhages
What do the cysts associated with adult P. kellitcoti look like?
reddish purple cysts 2-3cm in lung paranchyma, contain brownish fluid
thick wall
often near lung surface
what is the pathology of adult P. kellicoti flukes?
In the lungs so…
chronic bronchitis- hyperplasia of epithelium
chronic eosinophilic granulomatous pneumonia associated w. degenerating eggs in alveoli
How is Paragonimus kellicoti diagnosed?
detect eggs in feces, sputum, or tracheal wash by flotation or sedimentation
detect cysts in the lungs w/ radiographs