Treatment For Bronchail Asthma

Question 1

Asthma is a condition caused by

Answer 1

Hypersensitivity of the bronchus which leads to inflammation

Question 2

Methylxanthine drugs for asthma includes

Answer 2

Aminophylline
Theophylline

Question 3

Classes of drugs used to treat asthma include ( mention 7)

Answer 3

1) Beta Adrenergic agonist drug
2) Muscarinic/anticholinergic antagonist drug
3) mast cell stabilizers
4) Leucotrines receptor inhibitor
5) lipoxygenase inhibitor
6) anti IG E drug

Question 4

SAMA drugs include ( short acting Muscarinic antagonist drug )

Answer 4

Ipratropium

Question 5

LAMA drugs include ( long acting Muscarinic antagonist drug )

Answer 5

Titotropium

Question 6

Zilueton is a drug used for
And it’s mechanism of action

Answer 6

An asthma drug

It does it by inhibiting lipoxygenase enzyme ( in Leucotrines synthesis)

Question 7

SABA drugs include ( short acting beta 2 Adrenergic agonist drug )

Answer 7

Salbutamol( Albuterol)
Levabuterol
Terbutaline
Metaproterenol
Pirbuterol

Question 8

LABA drugs include ( long acting beta Adrenergic agonist drug )

Answer 8

Salmeterol
Vilaterol
Formoterol

Question 9

Mechanism of action of beta Adrenergic drugs in asthma is

Answer 9

Increase CAMP in the cell leading to relaxation of respiratory tract

Question 10

Methylxanthine mechanism of action is

Answer 10

Inhibiting phosphodiesterase ( an enzyme that cuts CAMP to AMP )

Thereby increasing the half life of Camp

Question 11

Which of these is not an asthma drug

Aminophylline
Clofazimine
Montelukast
Ipratropium

Answer 11

Clofazimine

Question 12

Leucotrine receptor inhibitior drug include

Answer 12

Montelukast
Zafirlukast

Question 13

Mast cell stabilizer drugs include

Answer 13

Nedocromil sodium
Sodium chromoglycate

Question 14

Anti IGE drugs include

Answer 14

Omelizumab

Question 15

Omelizumab

Answer 15

Is an asthma drugs that inhibits IGE antibody secretion

Question 16

Short acting beta 2 agonist drug used to treat asthma is

Answer 16

Albuterol
Levabuterol

Question 17

Inhaled corticosteroids used to treat asthma is

Answer 17

Beclomethasone
Budesonide
Ciclesonide
Flunisolide
Triamcinalone

Question 18

Mast cell stabilizers include

Answer 18

Nedocromil
Cromolyn

Question 19

What reduces FEV1?

Answer 19

Inflammation enzymes

Histamine
Prostaglandin
Trypase
Leucotrine
Platelet activating factor

Question 20

What is FEV??

Answer 20

This is also called forced expiratory volume

The amount of air one can exhale after a forced inspiration

Question 21

Non selective adrenoreceptor drugs in asthma treatment is

Answer 21

Epinephrine
Ephedrine

Question 22

What is the side effect of using epinephrine in treating asthma

Answer 22

Epinephrine binds to both alpha and beta blockers

It can bind to beta 1 and cause tachycardia, arrhythmia, worsen angina pectoris

Question 23

Non selective beta agonist

Salbutamol
Caffeine
Isoproterenol
Levabuterol
Loperamide

Answer 23

Isoproterenol / isoprenaline

Question 24

Beta 2 agonist mechanism of action on treating asthma

Answer 24

They activate adenyl cyclase which increases Camp causing bronchodilatoin

Question 25

Tachyphylaxis is defined as

Answer 25

Sudden increase in tolerance to a drug Cure it by increasing the dose

Question 26

Drugs that are Methylxanthine are

Answer 26

Aminophylline (theophylline) Caffeine Theobromine

Question 27

Side effect of Methylxanthine include

Answer 27

Cns- drowsiness tremor insomnia convulsion Cardiac- hypotension tachycardia arrhythmia palpitation Kidney- diuresis Git- vomiting diahreeal aggravates peptic ulcer

Question 28

Methylxanthine are preferably used to treat

Answer 28

COPD ( chronic obstructive pulmonary disease)

Question 29

Anticholinergices include

Answer 29

Ipratropium (short acting) Titotropomium ( long acting)

Question 30

Zilueton ;

Answer 30

Inhibits 5-lipoxygenase enzyme

Question 31

Ketotifen;

Answer 31

Mast cell stabilizer that inhibits H1 Histamine receptor blocker

Question 32

A mast cell stabilizer used a prophylactic drug is ———

Answer 32

Sodium chromoglycate

Question 33

Sodium chromoglycate is used in the treatment of

Answer 33

Allergic asthma Allergic conjunctivitis Allergic rhinitis Allergic dermatitis

Question 34

Glucocorticoids MOA in asthma is

Answer 34

They secrete lipocortin which inhibits phospholipase a2 Inhibiting the synthesis of Thromboxane, prostaglandin

Question 35

Side effects of glucocorticoids

Answer 35

Cause edema ( retains sodium and water ) Osteoporosis Cause hypertension

Question 36

Which of these does not have bronchodilation properties Albuterol Aminophylline Sodium chromoglycate Titotropium

Answer 36

Sodium chromoglycate

Question 37

Montelukast mechanism of action

Answer 37

They are leucotrine receptor antagonist by competitively blocking cystienyl leucotrines ( LTC4,LTD4,LTE4)

Question 38

Inhaled glucocorticoids include

Answer 38

Beclamethasone Fluticasone Flunisolide Budesonide Traimcinalone

Question 39

Systematic corticosteroids used in asthma is

Answer 39

Prednisone Predisolone Hydrocortisone

Question 40

Drugs used to treat severe acute asthma ( asthamticus) is

Answer 40

Systemic glucocorticoids; hydrocortisone Nebulized oxygen Anticholinergice Selective beta 2 agonist Iv fluid to cure dehydration

Question 41

Status asthmaticus also known as ————— is treated with

Answer 41

Severe acute asthma attack Iv hydrocortisone

Question 42

Isoprenaline ;

Answer 42

A non selective beta agonist drug Also called Isoproterenol