Transport of O2 and CO2 in Blood

Question 1

Oxygen is physically ________ in the blood and chemically __________ to hemoglobin

Answer 1

DISSOLVED

COMBINED

Question 2

Carbon dioxide is physically dissolved in the blood proteins as _________-_______ and _________

Answer 2

CARBAMINO COMPOUNDS

BICARBONATE

Question 3

What % of hemoglobin is saturated with O2 when exiting the capillaries?

Answer 3

97%

Question 4

What % of hemoglobin is saturated with O2 when entering the capillaries?

Answer 4

75%

Question 5

If cells utilize more oxygen than normal, what happens to the gradient?

Answer 5

The gradient increases, which increases flow of O2 from the blood to the tissues. Also increase in blood flow and increase metabolism

Question 6

Tissue PO2 is a function of:

Answer 6

1. Rate of O2 transport to tissues in blood
2. Rate at which the tissues use O2

Question 7

What are the two ways in which oxygen is transported?

Answer 7

1. Bound to hemoglobin -
   98% of O2 is bound to hemoglobin
2. Dissolved in plasma -
   2% of total O2 is dissolved in plasma

Question 8

How many subunits are the Hemoglobin A molecule?

Answer 8

4 subunits
- each bind 1 O2 molecule. The Heme group has iron (Fe2+) that binds to O2

Question 9

What dictates the amount of O2 bound to hemoglobin? There are 2 things

Answer 9

Amount dissolved
AND
# of binding sites in RBC

Question 10

CaO2 = the mL of O2 that is carried by oxyhemoglobin PLUS mL of