Transport across membranes Flashcards

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1
Q

What does the plasma membrane define

A

borders of cells and most organelles

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2
Q

How permeable is the membrane

A

Partially permeable

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3
Q

What does it mean if the membrane is partially permeable

A

the membrane allows some materials to freely enter or leave the cell/organelle while other materials cannot move freely

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4
Q

What does a phospholipid molecule consist of

A
  • glycerol
  • 2 fatty acids
  • phosphate-linked head group
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5
Q

What’s the thickness of a phospholipid

A

5-10nm in thickness

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6
Q

Where does the hydrophilic phospholipid head face

A

outwards and the hydrophobic fatty acids faces inwards

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7
Q

What is cholesterol

A

A lipid that sits with phospholipids in the core of the membrane

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8
Q

Where is cholesterol not found

A

in bacterial cell membranes

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9
Q

What affect do cholesterol molecules have on the membrane

A

makes it more rigid

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10
Q

What does cholesterol help maintain

A

Shape of animal cells

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11
Q

What does the phospholipid bilayer form

A

the ‘fluid’ part of the ‘fluid mosaic’ model

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12
Q

What’s the ‘mosaic’ part made up of

A

various proteins, carbohydrates and lipid molecules that punctuate membranes

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13
Q

What’re membrane bound molecules

A

Large molecules embedded in the bilayer

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14
Q

What can the bilayer form

A

open pores

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15
Q

What do open pores allow

A
  • diffusion of large molecules across the bilayer

- transport proteins that bind to specific molecules and carry them across the membrane

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16
Q

What does the glycolipid act as

A

A recognition site for toxins

17
Q

On the plasma membrane what part points outwards

A

hydrophilic heads of phospholipid molecules

18
Q

What part of the membrane points inwards

A

The hydrophobic part

19
Q

What do the glycoproteins do in the plasma membrane

A

branching carb of a protein which acts as a recognition site for chemicals

20
Q

What’s cholesterol needed for in the cell membrane

A

stability and flexibility

21
Q

What’re the 2 proteins found in the membrane

A
  • intrinsic

- extrinsic

22
Q

What’re 2 examples of intrinsic proteins

A
  • channel proteins

- carrier proteins

23
Q

What do channel proteins provide

A

hydrophilic channel that allows the passive movement of polar molecules and ions

24
Q

What holds channel proteins in place

A

interactions between hydrophobic core of the membrane and hydrophobic R-groups on the outside

25
Q

What do carrier proteins have an important role in

A

both passive transport and active transport into cells

26
Q

What do carrier proteins affect

A

shape of the protein changing

27
Q

What type of proteins are glycoproteins

A

Intrinsic proteins

28
Q

Where is the glycoprotein located

A

cell surface membrane with attached carb chains of various length and shape

29
Q

What do glycoproteins play the role in

A

cell adhesion and as receptor for chemical signals

30
Q

What’s cell signalling

A

when chemicals bind to the receptor causing a response from the cell which sets of a cascade of events inside the cell

31
Q

What’re 2 examples from cell signalling

A
  • receptors for neurotransmitters (acetylcholine at nerves)

- Receptors for peptide hormones (insulin and glucagon

32
Q

What’re glycolipids

A

lipids with attached carbohydrate chains

33
Q

What’re glycolipids known as

A

cell markers or antigens and can be recognised by cells of the immune system