Transmembrane proteins, golgi and COP Flashcards
How are transmembrane proteins integrated into a membrane?
Proteins with a signal anchor are threaded through a channel in the ER until its released into the membrane
What are the main elements of the golgi aparatus?
1) Cis Golgi Network
2) Medial golgi network
3)Trans Golgi Network
cisternae
layers/steps of the golgi aparatus
What is the role of the CGN
Decides if the vesicle goes back to ER or continues to next golgi station
Whats the role of the TGN
Sorts into different vesicles and begins vesicular transport
What are the endocytic pathways
Can to back to ER lumen or return to golgi aparatus for further modification
Material moves from ER to golgi to other compartments in the ……. direction
proximal to distal
What do coat proteins do? [2]
1) Facilitate transport
2) coatomers attach to membrane and pinch off a vesicle
What does COPII do
Forward transport— from ER to Golgi
What does COPI do
retrograde transport—golgi to ER