Neucleus, Neuclear import and neucleolus

Question 1

Nucleus function

Answer 1

1) Storage, replication and repair of genetic material
2) Expression of genetic material
3) Ribosome biosynthesis in neucleolus

Question 2

Nuclear structure

Answer 2

1) Envelope (membrane, pores, lamina)
2) Content (Chromatin, nucleoplasm, nucleolus)

Question 3

What is a nuclear localization signal?

Answer 3

-Several positively charged amino acids in the protein sequence
-Targets proteins to the nucleus

Question 4

Nuclear import process [5]

Answer 4

1) Protein w NLS interacts with importin in cytoplasm
2) Cargo/importin enters nucleoplasm
3) Interacts with Ran-GPT, and then dissociates and stays in nucleoplasm
4) Ran-GPT exits and importin finds new gpt