Endocytosis, autophagy and cytoskeleton Flashcards
What is clatherin
Clatherin coated vesicles move from TGM to other vesicles (lysosomes, endosomes, vacuoles)
Lysosome Functions [2]:
1) Autophagy
2) Degradation
Plant vacuole function
1) Regulates pressure
2) Mechanical support
3) Intracellular digestion
Cytoskeleton functions [4]
1) Structural support
2) Spatial organization
3) Intracellular transport
4) Contractility and motility
Components of cytoskeleton
1) Microfilaments
2) Microtubules
3) Intermediate filaments
What are microtubules made of
Turbulin dimer
What are microfilaments made of
Actin
Types of microtubules [2]
Axonemal (organized)
Cytoplasmic (loose)
Types of MT proteins [2]
motor
non motor
What do motor MT proteins do
Power intracellular transport
Kinesin or dynein
uses ATP to generate force
What do non motor MT proteins do
Control MT organization
Movement down a MT
1) ATP binds to leading head and swings tailing head 180 degrees in front
2) New head releases ADP which moves cargo forwards
3) Tailing head releases ATP which hydrolyzes into ADP and detaches it
4) ATP binds to head and process repeats
What types of Actin are there
G-actin (globular)
F-actin (filament)
Most important types of MTOC
1) Basal bodies associated with cilia and flagella
2) Centrosomes associated with spindle formation
Properties of intermediate filaments
1) non polar
2) Provide mechanical and structural support
