Translation Flashcards
1
Q
Splicing is done by:
A
snRNP
2
Q
5 cap is
A
pppN
3
Q
3’ Poly a tail + ENZYME involved
A
AAUAA + OH –> AAA (polyadenylate polymerase)
4
Q
Alt splicing example
A
fibronectin
5
Q
WT1 mutation at which bases:
A
GC & AT
6
Q
Wilm tumor + fraiser gene mutation?
A
WT1
7
Q
Fraiser- issue
A
KTS –> Aberrant splicing
8
Q
HPGS issue- deletion + exon + protein involved
A
50 AA deletion -> exon 11 prelamin A
9
Q
Castor beans –> which base is effected and what is also effected which subunit of ribosome
A
28s - Adenine
10
Q
What is in castor:
A
ricin
11
Q
mRNA half life is determined by tail- and what effects tail half life?
A
UTR
12
Q
Where is shine dalgro?
A
before AUG
13
Q
What is AUG?
A
start codon
14
Q
Stop codon is….
A
UAG & UAA & UGA
15
Q
Shine dalgro bind to:
A
16s rRNA
16
Q
What binds to small subunit is transcription?
A
IL 1 +2+3
