DNA replication Flashcards
1
Q
DNA G:
A
primase
2
Q
Topo 1 inhibitor:
A
amptothecin
3
Q
Topo 2 inhibitor:
A
doxorubixin + etoposide
4
Q
Ori C has _ DNA boxes with _ rich regions:
A
5; AT
5
Q
Primase is…
A
DNA dependent RNA primase
6
Q
Phase of DNA replication
A
S phase
7
Q
Point of SSB:
A
prevent annealing
8
Q
3’ to 5’ exonuclease activity (5’3’):
A
DNA polymerase
9
Q
Replisome function:
A
make leading + lagging strand
10
Q
Unit in DNA polymerase: (Alpha/beta/delta/ sigma)
A
beta
11
Q
Does DNA polymerase build new strand from scratch?
A
no
12
Q
Replication error chance
A
10^-3
13
Q
Proofreading error chance:
A
10^-6
14
Q
MMR error chance:
A
10^-9
