DNA damage + repair Flashcards
1
Q
BER- cause, enzyme + base changes
A
ROS; glycolase; G to T
2
Q
NER- causes, solution
A
xeroderma pigmentosum; base flip
3
Q
Example of chemical instability
A
depurination + deamination of cytosine
4
Q
How TLS works:
A
has large active site and swaps with machinery
5
Q
MMR disease
A
colorectal carcinoma
6
Q
Non-homologus- stage; disease
A
G1 ; leukemia
7
Q
Homologus- stage; needs
A
S-G2; RAD51