DNA damage + repair Flashcards

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1
Q

BER- cause, enzyme + base changes

A

ROS; glycolase; G to T

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2
Q

NER- causes, solution

A

xeroderma pigmentosum; base flip

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3
Q

Example of chemical instability

A

depurination + deamination of cytosine

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4
Q

How TLS works:

A

has large active site and swaps with machinery

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5
Q

MMR disease

A

colorectal carcinoma

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6
Q

Non-homologus- stage; disease

A

G1 ; leukemia

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7
Q

Homologus- stage; needs

A

S-G2; RAD51

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