Lecture 1 - reminders Flashcards

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1
Q

(1) Topoisomerase job

A

cleaving + uncleaving

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2
Q

(1) Etoposide job

A

stop topoisomerase –> cancer treatment

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3
Q

(1) Quinolone job

A

stop DNA gyrase

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4
Q

(1) Burkitt lymphoma gene

A

myc –> IgH, IgK, IgL

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5
Q

(1) Nonactive chromatin

A

heterochromatin

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6
Q

(1) Active chromatin

A

euchromatin

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7
Q

(1) Between 2 radical domains is:

A

30 nm

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8
Q

(1) Base pair made of:

A

nitrogen

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9
Q

(1) Chargaff rule:

A

AT GC

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10
Q

(1) Chromosome conformation capture

A

map physical contact between different parts of genome –> each chromosome is @ a chromosome territory

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11
Q

(1) Replication direction is:

A

5’3’

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