Cancer 1 + 2 Flashcards
1
Q
SNV e.g:
A
BRAFV600E –> tyrosine kinase issue
2
Q
BCR is at which chromosome
A
22
3
Q
ABL is at which chromosome
A
9
4
Q
Philidalphia chromosome effects which leukemia
A
myeloid
5
Q
HPV effect:
A
E6 + E7
6
Q
Aflatoxin effects:
A
liver
7
Q
BRCA 1 / 2 NHEJ?
A
1
8
Q
No. cancer genes
A
719
9
Q
PTEN job is to stop
A
GF
10
Q
P53 job is to cause
A
apoptosis
11
Q
How many mutations needed for cancer?
A
1-10
12
Q
BRCA 1 recessive/ dominant?
A
Recessive
13
Q
Deregulation in cancer effects which genes
A
RAS + GF
14
Q
Amplify in cancer these…
A
myc + cyclin d
15
Q
Which makes faster cancer myc or RAS?
A
RAS
