translation Flashcards

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1
Q

In translation, mRNA base triplets (__________) are read in 5’ to 3’direction. Each codon specifies an amino acid. __________ (transfer RNA) has an anticodon on one end (complement to codon) and a corresponding amino acid on the other end and adds amino acids to growing polypeptide chain

A

In translation, mRNA base triplets (codon) are read in 5’ to 3’direction. Each codon specifies an amino acid. tRNA (transfer RNA) has an anticodon on one end (complement to codon) and a corresponding amino acid on the other end and adds amino acids to growing polypeptide chain

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2
Q

Most codons code for one of the 20 amino acids. 3 codons code for translation to stop(UAA UAG UGA). Translation always begins with the codon, methionine (AUG), which determines the reading frame.

A

Most codons code for one of the 20 amino acids. 3 codons code for translation to stop(UAA UAG UGA). Translation always begins with the codon, methionine (AUG), which determines the reading frame.

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3
Q

Translation occurs on __________ that have two subunits and 3 binding sites for tRNA.

A

Translation occurs on protein that have two subunits and 3 binding sites for tRNA.

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4
Q

__________ are changes in genetic material which may occur due to errors in DNA copying or from mutagens.

A

mutations are changes in genetic material which may occur due to errors in DNA copying or from mutagens.

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5
Q

Substitution mutations are categorized as __________ if no change in the amino acid sequence occurs, __________ if a different amino acid is coded, or __________ if the mutation codes for a stop codon.

A

Substitution mutations are categorized as slience if no change in the amino acid sequence occurs, missense if a different amino acid is coded, or nonsense if the mutation codes for a stop codon.

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6
Q

In translation, mRNA base triplets (codons) are read in 5’ to 3’ direction. Each codon specifies an amino acid. tRNA(transfer RNA) has an anticodon on one end(complement to codon) and a corresponding amino acid on the other end and adds amino acids to growing polypeptide chain.

A

In translation, mRNA base triplets (codons) are read in 5’ to 3’ direction. Each codon specifies an amino acid. tRNA(transfer RNA) has an anticodon on one end(complement to codon) and a corresponding amino acid on the other end and adds amino acids to growing polypeptide chain.

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7
Q

Transcription- synthesis of messenger RNA (mRNA) using information in DNA •Translation- synthesis of a polypeptide using information in the mRNA

A

Transcription- synthesis of messenger RNA (mRNA) using information in DNA •Translation- synthesis of a polypeptide using information in the mRNA

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8
Q

In translation, mRNA base triplets (codons) are read in 5’ to 3’ direction. Each codon specifies an amino acid. tRNA(transfer RNA) has an anticodon on one end(complement to codon) and a corresponding amino acid on the other end and adds amino acids to growing polypeptide chain.

A

In translation, mRNA base triplets (codons) are read in 5’ to 3’ direction. Each codon specifies an amino acid. tRNA(transfer RNA) has an anticodon on one end(complement to codon) and a corresponding amino acid on the other end and adds amino acids to growing polypeptide chain.

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9
Q

Substitutions:
-Silent - no effect, new codon codes for same amino acid
Missense - codes for different amino acid
Nonsense - codes for stop codon
Insertion - addition of base pairs
Deletion - loss of base pairs
Frameshift mutation - occurs with insertion or deletion of base pairs that shifts reading frame

A

Substitutions:
-Silent - no effect, new codon codes for same amino acid
Missense - codes for different amino acid
Nonsense - codes for stop codon
Insertion - addition of base pairs
Deletion - loss of base pairs
Frameshift mutation - occurs with insertion or deletion of base pairs that shifts reading frame

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10
Q

The anticodon of a given tRNA can bind to one or a few specific mRNA codons.

A

The anticodon of a given tRNA can bind to one or a few specific mRNA codons.

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11
Q

ribosome:
3 binding sites for tRNA
Facilitate coupling of tRNA and mRNA
2 subunits made of proteins and rRNA (ribosomal RNA

A

ribosome:
3 binding sites for tRNA
Facilitate coupling of tRNA and mRNA
2 subunits made of proteins and rRNA (ribosomal RNA

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12
Q

Polyribosomes:

Multiple ribosomes can translate single mRNA simultaneously

A

Polyribosomes:

Multiple ribosomes can translate single mRNA simultaneously

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13
Q

In prokaryotes transcription and translation occur simultaneously

A

In prokaryotes transcription and translation occur simultaneously

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14
Q
16. Explain how antibiotics target transcription and translation
Target ribosome (different structure in bacteria and humans)
Streptomycin change shape of the 30s portion, cause node on mRNA to be read incorrectly.
A
16. Explain how antibiotics target transcription and translation
Target ribosome (different structure in bacteria and humans)
Streptomycin change shape of the 30s portion, cause node on mRNA to be read incorrectly.
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15
Q

Mutations are changes in genetic material which may occur due to errors in DNA copying or from mutagens.

A

Mutations are changes in genetic material which may occur due to errors in DNA copying or from mutagens.

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