translation Flashcards
In translation, mRNA base triplets (__________) are read in 5’ to 3’direction. Each codon specifies an amino acid. __________ (transfer RNA) has an anticodon on one end (complement to codon) and a corresponding amino acid on the other end and adds amino acids to growing polypeptide chain
In translation, mRNA base triplets (codon) are read in 5’ to 3’direction. Each codon specifies an amino acid. tRNA (transfer RNA) has an anticodon on one end (complement to codon) and a corresponding amino acid on the other end and adds amino acids to growing polypeptide chain
Most codons code for one of the 20 amino acids. 3 codons code for translation to stop(UAA UAG UGA). Translation always begins with the codon, methionine (AUG), which determines the reading frame.
Most codons code for one of the 20 amino acids. 3 codons code for translation to stop(UAA UAG UGA). Translation always begins with the codon, methionine (AUG), which determines the reading frame.
Translation occurs on __________ that have two subunits and 3 binding sites for tRNA.
Translation occurs on protein that have two subunits and 3 binding sites for tRNA.
__________ are changes in genetic material which may occur due to errors in DNA copying or from mutagens.
mutations are changes in genetic material which may occur due to errors in DNA copying or from mutagens.
Substitution mutations are categorized as __________ if no change in the amino acid sequence occurs, __________ if a different amino acid is coded, or __________ if the mutation codes for a stop codon.
Substitution mutations are categorized as slience if no change in the amino acid sequence occurs, missense if a different amino acid is coded, or nonsense if the mutation codes for a stop codon.
In translation, mRNA base triplets (codons) are read in 5’ to 3’ direction. Each codon specifies an amino acid. tRNA(transfer RNA) has an anticodon on one end(complement to codon) and a corresponding amino acid on the other end and adds amino acids to growing polypeptide chain.
In translation, mRNA base triplets (codons) are read in 5’ to 3’ direction. Each codon specifies an amino acid. tRNA(transfer RNA) has an anticodon on one end(complement to codon) and a corresponding amino acid on the other end and adds amino acids to growing polypeptide chain.
Transcription- synthesis of messenger RNA (mRNA) using information in DNA •Translation- synthesis of a polypeptide using information in the mRNA
Transcription- synthesis of messenger RNA (mRNA) using information in DNA •Translation- synthesis of a polypeptide using information in the mRNA
In translation, mRNA base triplets (codons) are read in 5’ to 3’ direction. Each codon specifies an amino acid. tRNA(transfer RNA) has an anticodon on one end(complement to codon) and a corresponding amino acid on the other end and adds amino acids to growing polypeptide chain.
In translation, mRNA base triplets (codons) are read in 5’ to 3’ direction. Each codon specifies an amino acid. tRNA(transfer RNA) has an anticodon on one end(complement to codon) and a corresponding amino acid on the other end and adds amino acids to growing polypeptide chain.
Substitutions:
-Silent - no effect, new codon codes for same amino acid
Missense - codes for different amino acid
Nonsense - codes for stop codon
Insertion - addition of base pairs
Deletion - loss of base pairs
Frameshift mutation - occurs with insertion or deletion of base pairs that shifts reading frame
Substitutions:
-Silent - no effect, new codon codes for same amino acid
Missense - codes for different amino acid
Nonsense - codes for stop codon
Insertion - addition of base pairs
Deletion - loss of base pairs
Frameshift mutation - occurs with insertion or deletion of base pairs that shifts reading frame
The anticodon of a given tRNA can bind to one or a few specific mRNA codons.
The anticodon of a given tRNA can bind to one or a few specific mRNA codons.
ribosome:
3 binding sites for tRNA
Facilitate coupling of tRNA and mRNA
2 subunits made of proteins and rRNA (ribosomal RNA
ribosome:
3 binding sites for tRNA
Facilitate coupling of tRNA and mRNA
2 subunits made of proteins and rRNA (ribosomal RNA
Polyribosomes:
Multiple ribosomes can translate single mRNA simultaneously
Polyribosomes:
Multiple ribosomes can translate single mRNA simultaneously
In prokaryotes transcription and translation occur simultaneously
In prokaryotes transcription and translation occur simultaneously
16. Explain how antibiotics target transcription and translation Target ribosome (different structure in bacteria and humans) Streptomycin change shape of the 30s portion, cause node on mRNA to be read incorrectly.
16. Explain how antibiotics target transcription and translation Target ribosome (different structure in bacteria and humans) Streptomycin change shape of the 30s portion, cause node on mRNA to be read incorrectly.
Mutations are changes in genetic material which may occur due to errors in DNA copying or from mutagens.
Mutations are changes in genetic material which may occur due to errors in DNA copying or from mutagens.