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Therapeutics > TPX Neuro > Flashcards

TPX Neuro Flashcards

1
Q

GABA Modulators

A

Barbiturates (prolong opening, some blockade of glutamate receptors)
Benzodiazepines (increase frequency)

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2
Q

Tiagabine

A

Inhibits GABA reuptake

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3
Q

Vigabatran

A

Inhibits GABA-transaminase

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4
Q

Barbiturates

A

Prolong opening of GABA-mediated channels

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5
Q

Benzodiazepines

A

Increase frequency of GABA-mediated channels

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6
Q

Na Channel Inhibitors

A

Carbamazepine, oxcarbazepine, phenytoin, lamotrigine, zonisamide

Lacosamide (hinged lid)

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7
Q

Lamotrigine

A

Some kainate activity

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8
Q

Zonisamide

A

Na channels, T-type Ca channels, and CA inhibitor

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9
Q

Valproate

A

Na channels, T-type Ca channels, GABA enhancement

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10
Q

Felbamate

A

Block NMDA receptor, GABA enhancement

Black box warning

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11
Q

Gabapentin

A

Blocks Ca channels
Suppresses NMDA at glycine site

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12
Q

Pregablin

A

Blocks Ca channels
Stimulates glutamic acid decarboxylase

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13
Q

Topiramate

A

Block Na channels
GABA modulator
Glutamate receptor antagonist
CA inhibition

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Therapeutics (11 decks)

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