Cardio Exam 1 Medchem Flashcards
Cholinergic Agonists
Direct:
-acetylcholine
-carbachol
-bethanocol
-pilocarpine
-Cevimeline
Indirect:
Reversible:
-physostigmine
-neostigmine
-pyridostigmine
-edrophonium
Irreversible:
-echothiophate
Cholinergic Antagonists
Muscarinic:
-atropine
-tropicamide, cyclopentolate, homatropine, atropine
-oxybutynin
-scopolamine
-ipratropium
-benztropine
Ganglionic Blockers:
-botulinum
Nicotinic:
non-depolarizing
-tubocrurine
-cisatrcurium
-pancuronium
depolariazing
-succinylcholine
Carbachol
Direct acting cholinergic agonist
Glaucoma
Bethanochol
Direct acting cholinergic agonist
treats post-operative urinary retention
*selective for muscarinic
Pilocarpine
Direct acting cholinergic agonist
glaucoma, dry mouth
*no longer used
*selective for muscarinic
Cevimeline
direct acting cholinergic agonist
dry mouth
*selective for m1 and m3
physostigmine
Reversible cholinesterase inhibitor
-glaucoma, reverse atropine
neostigmine
Reversible cholinesterase inhibitor
-myasthenia gravis, post-operative urinary retention
pyridostigmine
Reversible cholinesterase inhibitor
-myasthenia gravis
Edrophonium
Reversible cholinesterase inhibitor
-was used to treat myasthenia gravis
Echothiophate
Irreversible cholinesterase inhibitor
-glaucoma
Atropine
Cholinergic Antagonist- anti-muscarinic
-retinal exams, bradycardia
Tropicamide, cyclopentolate, homatropine
Cholinergic Antagonist- anti-muscarinic
-eye exams
Scopolamine
Cholinergic Antagonist- anti-muscarinic
-motion sickness
Ipatropium
Cholinergic Antagonist- anti-muscarinic
-COPD and nasal discharge
oxybutynin
Cholinergic Antagonist- anti-muscarinic
-overactive bladder
Benztropine
Cholinergic Antagonist- anti-muscarinic
-parkinsons
Botulinum toxin
ganglionic blocker
tubocurarine, cisatracurium, pancuronium
Cholinergic Antagonist- anti-nicotinic
-surgical procedures
*non-depolarizing
succinylcholine
Cholinergic Antagonist- anti-nicotinic
-surgical procedures
*depolarizing agent
Adrenergic Agonists
-epinephrine
-norepinephrine (less beta-2, beta-3)
alpha-1:
phenylephrine
midodrine
alpha-2:
-clonidine
-oxymetazoline
Beta:
-isoproterneol
1-dobutamine
2-albuterol
3-mirabegron
Mixed:
-ephedrine
-pseudophedrine
Indirect: amphetamine
Phenylephrine
alpha-1 selective adernergic agonist
-hypotension, nasal decongestant (no longer used), and dilating pupils
Midodrine
alpha-1 selective adernergic agonist
-hypotension
Clonidine
alpha-2 selective adrenergic agonist
-hypertension, severe pain, and ADHD
oxymetazoline
alpha-2 selective adrenergic agonist
-deconngestant
isoproteronol
Beta-selective agonist
-bronchospasms in COPD
dobutamine
beta-1 selective agonist
-acute heart failure, cardiogenic shock
Albuterol
beta-2 selective agonist
-asthma
Mirabegron
beta-3 selective agonist
-overactive bladder
ephedrine and pseudophedrine
Mixed acting sympathomimetics
-ephedrine no longer used
-decongestant
amphetamine
indirect acting sympathomimetics
Adrenergic antagonists
alpha:
-phenoxybenzamine (irreversible)
-prazosin, doxazosin, terazosin
Beta:
-propranolol
-atenolol
Mixed:
-labetolol
-carvedilol
phenoxybenzamine
irreversible alpha-blocker
-pheochromocytoma
prazosin, terazosin, doxazosin
reversible alpha blocker
-mild to moderate htn, benign prostatic hyperplasia
propranolol
beta-blocker
non-selective
atenolol and metoprolol
beta-blocker
selective for Beta-1
labetolol and carvedilol
beta-blocker
mixed affinity for alpha and beta
