Toxicology Flashcards

1
Q

Xenobiotic

A

Substances that are foreign to the body

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2
Q

Mode of ingestion

A

How a substance enters the body

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3
Q

LD 50

A

Lethal dose for 50% of the population

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4
Q

Opiates

A

Drugs obtained from opium

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5
Q

ADME

A

Absorption
Distribution
Metabolism
Excretion
(The process by which drugs and toxins move through the body)

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6
Q

C sub p

A

Peak plasma concentration

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7
Q

First-pass metabolism

A

Reduces concentration of a drug in the bloodstream; affects orally ingested drugs

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8
Q

Metabolites

A

Substance made or used when the body breaks down drugs

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9
Q

Central blood

A

Blood sample taken from the heart

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10
Q

Peripheral blood

A

Blood sample taken from a site away from the heart

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11
Q

Postmortem distribution

A

The concentration of toxins and metabolites can change after death

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12
Q

Immunoassays

A

Screening test based on the reaction between antigens and antibodies

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13
Q

Mass spectrometry

A

Measures the mass of a molecule after it converts the molecule to a gas-phase ion

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