TORCHES

Question 1

chorioretinitis + hydrocephalus + intracranial

calcifications

Answer 1

CMV

Question 2

maculopapular peeling rash, snuffles (rhinitis w/
serous, purulent, or bloody discharge), HSM,
jaundice, generalized LAD

Answer 2

early congenital syphillis

Question 3

limb hypoplasia, clear vesicles → cutaneous

scars, chorioretinitis, cortical atrophy

Answer 3

congenital varicella

Question 4

suspect w/ thrush, generalized LAD,

hepatomegaly, and FTT

Answer 4

neonatal HIV

Question 5

cataracts + deafness + PDA

Answer 5

rubella

Question 6

deafness, saber shins, mulberry molars,

Hutchinson teeth, saddle nose

Answer 6

late congenital syphillis

Question 7

vesicular rash, pneumonitis, temporal lobe

encephalitis (focal seizures)

Answer 7

HSV

Question 8

usually asx, MC sequelae is sensorineural
hearing loss
+ “blueberry muffin” rash, HSM/jaundice,
thrombocytopenia, periventricular calcifications

Answer 8

CMV

Question 9

how to dx neonatal HIV

Answer 9

HIV PCR!! (ELISA will be false + from mom’s Abs)

Question 10

how to diagnose congenital syphillis

Answer 10

screen with RPR/VDRL and confirm with TPPA or FTA-Abs

Question 11

Treatment of congenital syphillis

Answer 11

PCN

Question 12

Tx for neonatal HIV

Answer 12

ALL kids to HIV moms get ZDV but also give bactrim for PCP ppx

Question 13

Tx for congenital CMV

Answer 13

IV Ig and supportive care

Question 14

tx for congenital toxo

Answer 14

pyrimethamine and sulfadiazine