TORCH Infections Flashcards
Sx’s of toxoplasmosis?
asx, chorioretinitis, intracranial calcifications, fetal death, anemia, thrombocytopenia, jaundice, mental retardation, seizures
Dx of toxo?
not a routine screening unless HIV+, PCR, IgG, amniocentesis, skin test
Tx for toxoplasmosis?
Spiramycine (Rovamycine), pyrimethamine + leucovorin + sulfadiazine
Effects of syphilis (short and long term)
abortion/stillbirth/neonatal death, rash, jaundice, HSM, LAD, Hutchinson’s teeth, mulberry molars, saber shins, saddle nose
Dx tests for syphilis
Screen ALL women, non treponemal = VDRL/RPR, treponemal = FTA-ABS, TP-PA
Tx syphilis
PCN need 4 fold decrease in titer in 6mos, use RPR/VDRL to track for 1 yr
What are sx’s of rubella?
stillborn, death, microcephaly, blueberry rash, deaf, cataracts, encephalitis
Dx of rubella?
screen ALL women IgG/IgM. IMX before or after Pg, counsel if infected during
Hep B test/tx
ALL women screened HbsAg–get HbIg and vaccine, same for baby when born
When is HIV passed to the baby the most?
intrapartum
Tx HIV
All women screened, tx is HARRT. Cannot use EFavirenz, STAvudine/Didanosine, NEVirapine. No breastfeeding. “Never stay with elves for dinner.”
Herpes virus sx’s
microcephaly, hydrocephalus, chorioretinitis, vesicular skin lesions, retardation, blindness
Dx and Tx
No routine screening–hx and PE. acyclovir, c section if lesions present at birth
Complications of varicella in Pg
Routine screening. PNA, death, fetal death, limb atrophy, CNS damage. give VariZIG if exposed.
How do you treat Bacterial vaginosis in Pg?
oral or topical Flagyl or clindamycin
