Topic 72 (cAMP-mediated Signal Transduction) Flashcards
0
Q
Which enzyme produces cAMP and what is the substrate of this enzyme?
A
Adenylate cyclase; its substrate: ATP
1
Q
Name three second messenger mediating in signal transduction!
A
- cAMP
- DAG
- IP3
2
Q
What protein is the target of cAMP?
A
PKA
3
Q
Which enzyme inactivates cAMP?
A
cAMP phosphodiesterase/cyclic nucleotide phosphodiesterase
4
Q
Which transcription factor is the major substrate of protein kinese A?
A
CREB
5
Q
Name two types of proteins which are phosphorylated by PKA!
A
- Enzymes
- Transcription Factors
