Topic 63-65 (Cytosceleton) Flashcards
0
Q
List 3 function of cytosceleton!
A
- Cell movement
- Cell division
- Cell shape
1
Q
List the elements of cytosceleton (3)!
A
- Actin Filaments
- Intermediate Filaments
- Microtubules
2
Q
List the steps of actin polymerization!
A
G-actin –> neucliation –> elongation –> F-actin
3
Q
What kind of cells contain these types of intermediate filaments: perpherin, neurofilament, lamin?
A
- Peripherin; Glia cells
- Neurofilament; Neurons
- Lamins; All nucleus-containing cells
4
Q
Name a diesease caused by mutation of an intermediate filament gene and the name of the gene as well.
A
- Epidermolysis bullosa complex (cytokeratin)
- Familiar cardiomyopathy (desmin)
- Amyotrophic lateral sclerosis (neurofilament)
5
Q
Give an example for laminopathies!
A
Myopathies
6
Q
Name an agent which inhibits the polymerization of microtubules!
A
Colchicine
7
Q
Name two microtubule motor proteins!
A
- Kinesin
- Dyenin
8
Q
Which cytosceleton element is responsible for the movement of cilia?
A
Microtubules
9
Q
What are stress fibers made of?
A
Actin/microfilaments
10
Q
What are the 3 main features of Deuchenne muscular dystrophy?
A
- Lack of dystrophin protein
- Progressive muscle degeneration
- X-linked recessive inheritance
11
Q
List 3 actin binding proteins!
A
- Fimbrin
- Filamin
- Villin
