TOPIC 6 - anemia & blood transfusions Flashcards
blood disorders
iron deficiency
vitamin B12 deficiency
folic acid deficiency
sickle cell anemia
aplastic anemia
anemia is
a deficiency of the number of erythrocytes
change in quantity or quality of Hgb
change in volume of packed RBC (Hct)
causes of anemia
blood loss, impaired production of erythrocytes, increased destruction of erythrocytes
clinical manifestations are based on
rate at which anemia has evolved
severity
coexisting diseases
symptoms of anemia
fatigue, weakness, SOB, lightheadedness, pallor, palpitations, chest pain, angina, MI, dizzy, fainting, rapid HR, glossitis
normocytic anemia
aplastic or sickle cell anemia
CAUSES:
aplastic: inherited, leukemia, CKD, something taken into the body
sickle cell: inherited
clinical manifestations of sickle cell disease
fever, swelling, tenderness, tachypnea, HTN, nausea, vomiting
triggers for sickle cell episodes
hypoxia or deoxygenated RBC caused by:
viral or bacterial infection
high altitude
surgery
blood loss
dehydration
low body temp
microcytic anemia
iron deficiency or thalassemia
causes and risk factors for iron deficiency
inadequate intake of iron
poor GI absorption
blood loss (most common)
causes of thalassemia
inadequate Hgb production which decreases RBC production
s/s of thalassemia
physical and mental growth changes, pale and jaundice, splenomegaly, hepatomegaly, cardiomyopathy
treatment of thalassemia
blood transfusion and splenectomy
macrocytic anemia
vitamin B12 deficient or folic acid deficient
foods rich in folic acid
orange juice, romaine, spinach, liver, rice, barley, sprouts, wheat germ, beans, peanuts, broccoli, asparagus, peas, chickpeas, eggs, meats, poultry, milk, shellfish