topic 6 Flashcards
What are the two responses involved in specific immunity?
humeral response and cell mediated response
what is the specific immune response?
an antigen specific response
what do cytokines do in the humoral response?
activate B cells that the differentiate into either memory B cells of plasma cells
what do plasma cells do?
make antibodies
what do memory cells do?
give immunity by remembering the pathogen
how do antibodies help clear infection?
agglutinating pathogens, neutralising toxins and preventing the pathogen from binding to the human cells
what do cytokines do in the cell mediated response?
activate T cells which then differentiate into 3 types of cells.
what are the 3 cells T cells differentiate into?
killer T cells, helper T cells and memory cells
what do killer T cells do?
they bind to the infected body cell and produce perforin which causes cell lysis
what do helper T cells do?
release substances e.g. cytokines that help activate B cells, t killer cells and macrophages
what is splicing?
the process where introns are removed from pre- mRNA
what is alternative splicing?
when certain exons are removed, as well as the introns, to form different mRNA strands\
what does alternative splicing mean can happen?
more then one amino acid sequence and so more then one protein can be produced from one gene.
what is an intron?
section of genes that don’t code for amino acids
what is an exon?
the sections of genes that do code for amino acids
what is pre-mRNA?
mRNA strands that contain both introns and exons
name barriers to infection
skin, stomach acid, lysozyme, gut and skin flora.
what triggers an immune response
foreign antigens
three steps of the non-specific immune response
inflammation, production of interferons, phagocytosis