topic 5: circulatory system Flashcards

1
Q
  1. List the three layers of the heart wall and describe the pericardial cavity.
A

Endocardium: Inner layer, smooth, lines the chambers
* Myocardium: Middle, muscular layer, responsible for contraction
* Epicardium: Outer layer, part of the heart’s protective sac
Pericardium consists of two layers.
* Inner visceral pericardium= epicardium, forms the outer surface of the
heart.
between is perciarial cavity containing pericaridal fluid
* Outer parietal pericardium is a thin and semitransparent membrane enclosing the
heart.

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2
Q
  1. What are the locations and functions of each tricuspid valves?
A

tricuspid valve: Situated between the right
atrium and right ventricle. Composed of three leaflets or
cusps.
function: Prevents backflow of
blood from the right ventricle to
the right atrium during
ventricular contraction.

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3
Q

What are the locations and functions of mitral valves?

A

Located
between the left atrium and left
ventricle.Bicuspid valve, having two
cusps.
function: Prevents backflow of blood
from the left ventricle to the left atrium
during ventricular contraction

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4
Q

What are the locations and functions of pumonary valves?

A

Located
at the entrance to the pulmonary
artery.Comprises
three semilunar cusps
function: Opens during right
ventricular contraction to allow
blood flow into the pulmonary
artery and prevents backflow into
the right ventricle

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5
Q

What are the locations and functions of aortic valves?

A

Positioned at the junction of the left
ventricle and the aorta. Comprises
three semilunar cusps.
function: Opens to allow
oxygenated blood to flow from the
left ventricle into the aorta; closes to
prevent backflow.

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6
Q

What are the differences among arteries, veins and capillaries in terms of the structures and functions?

A

arteries: thick wall, carry oxygenated blood away from heart
veins: thinner walls, have valves, return deoxygenated blood to heart
capillaries: single cell thick, exchange of gases, nutrients, waste between blood and tissue

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7
Q

what are the two parts that make up the cardiac cycle

A

-systole and diastole

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8
Q

what happens during systole

A
  • Ventricles contract
  • pushing blood into the aorta and pulmonary artery.
  • Semilunar valves open.
  • AV valves close to prevent backflow.
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9
Q

what happens during diastole

A

Ventricles relax
* blood filling the ventricles.
* The AV valves (tricuspid and mitral) are open,
* while the semilunar valves (aortic and pulmonary) are closed.
* atria contract

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10
Q

mechanism of the pumonary circulation

A
  • Right Ventricle to Lungs: Deoxygenated blood from the body enters the
    right atrium of the heart and is pumped into the right ventricle. From the
    right ventricle, it is pumped through the pulmonary artery to the lungs.
  • Gas Exchange in the Lungs: In the lungs, carbon dioxide is released
    from the blood and oxygen is absorbed. This exchange occurs in the tiny
    air sacs in the lungs, known as alveoli.
  • Lungs to Left Atrium: The now oxygen-rich blood returns to the heart via
    the pulmonary veins, entering the left atrium.
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11
Q

mechanism of the systemic circulation

A

Left Ventricle to Body: Oxygen-rich blood is pumped from the left
ventricle into the aorta, the body’s main artery. From the aorta, blood
flows through a series of arteries, arterioles, and capillaries, reaching
every part of the body.
* Nutrient and Gas Exchange: In the capillaries, oxygen and
nutrients are delivered to tissues, and waste products like carbon
dioxide are collected.
* Return to the Heart: Deoxygenated blood then returns to the heart
through venules and veins, culminating in the cranial and caudal
vena cava, which empty into the right atrium of the heart.

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12
Q

function of the coronary circulation

A

supply oxygenated blood to heart muscle

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13
Q

what are the two different coronary arteries

A

-right coronary artery
-left coronary artery

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14
Q

mechanism of the coronary circulation

A

Oxygenated Blood to Heart Muscle: The coronary arteries branch
off the aorta near the point where the aorta and the left ventricle
meet. These arteries supply oxygen-rich blood to the heart muscle
itself.
* Veins Collect Deoxygenated Blood: After passing through the
capillaries in the heart muscle, the deoxygenated blood is collected
by the coronary veins.
* Return to Right Atrium: This blood is then returned to the right
atrium of the heart.

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15
Q

explain how blood flows through the heart

A

Deoxygenated blood from the body returns to the right atrium.
* Blood from the upper body returns to the cranial vena cava.
* Blood from the lower body returns to the caudal vena cava.
* As the RA is filled with blood, RV is relaxed, Tricuspid valve opens and
blood is filled into RV; RA contract, the rest blood is pumped into the RV.
* Once the right ventricle is filled with blood, Tricuspid valve closes to
prevent blood from flowing back into the atrium.
* RA then relaxes.
* RV contracts, pulmonary valve opens and blood is pumped into the
lungs where oxygenation takes place.
* Pulmonary valve then closes to prevent blood from flowing back to the
RV. Oxygen rich blood returns from the lungs to the LA. LV is relaxed, the
mitral valve opens and blood is filled into LV;
* LA contract, the rest blood is pumped into the LV.
* Once the LV is full, mitral valve closes, and LA relaxes.
* LV contracts, the aortic valve opens.
* Oxygen rich blood is pumped into the aorta to reach all parts of the
body.
* Aortic valve then closes to prevent blood from flowing back to the heart,
and LV relaxes

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16
Q
  1. Describe the electrical conduction system of the heart
A

-The heart’s electrical impulse begins in the
sinoatrial (SA) node (the heart’s natural
pacemaker), located in the right atrium.
-The impulse spreads through the atria,
causing both of them to contract and push
blood into the ventricles.
-The impulse then reaches the
atrioventricular (AV) node, where it
slows slightly, allowing the ventricles to fill
with blood
-From the AV node, the impulse travels
through the bundle of His, down the left
and right bundle branches, and through
the Purkinje fibers, causing the ventricles
to contract and pump blood to the lungs
and the rest of the body

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17
Q

describe the blood circulation in fish

A

The heart of fish has only TWO, in
stead of FOUR, chambers (one
Atrium and one Ventricle).
* The gas exchange is done is Gill
Capillaries.
* The oxygenated blood from Gill
capillaries flow straight a way to the
body tissues and
* deoxygenated blood from tissues
return to the atrium of the heart,
and then flow into the ventricle
complete the circulation.

18
Q

what is blood made out of

A

plasma and blood cells

19
Q
  1. What are the major components of plasma in the blood
A

Albumin (55%):Retain the fluid in the blood by osmosis Thus, preventing the water ‘leaking’ out into the extracellular spaces
-Fibrinogen (7%):Involved in the blood coagulation
-Immunoglobulin (38%):* Antibodies, produced by immune system to neutralize the
pathogens
-othersL enzyme, proteins

20
Q

what are the different types of blood cells

A

Red blood cells
(Erythrocytes)
* White blood
cells
(leukocytes)
* Platelets
(Thrombocytes)

21
Q

differenciate plasma vs serum

A

plasma: * prepared by centrifuging the
blood with anticoagulant, collection of supernantant (contains fibrinogen) aka whole blood - cells
serum: prepared by allowing blood to
clot on its ow, Collection of supernatant (no fibrinogen cos gor used up) (whole blood-cells-clotting factors)

22
Q
  1. What are the primary cell content and primary function of red blood cells?
A

-haemoglobin
function: transport o2 from lungs to tissue cells
co2 from tissue cells to lungs

23
Q
  1. Compare the colours of blood with or without oxygen.
A

Oxyhemoglobin
* bound with oxygen
* bright red (blood in artery)
Deoxyhemoglobin
* free of oxygen
* dark red (blood in vein)

24
Q

Dietary Requirements for Producing Red
Blood Cells

A

ron (red meat and organs, such as liver)
* vitamin B12 (source: animal-based foods)
* folic acid (Leafy green plant)

25
Q

where are erythrocytes made and destroyed

A

made in bone marrow
destroyed in spleen

26
Q

what are the two different kinds of leukocytes

A

Granulocytes
* Agranulocytes

27
Q

function of neutrophil

A

Increase in number during infection
* Migrate to the site of the infection to kill the
microbes.

28
Q

function of eosinophils

A

kill parasitic worms
* inactivate some inflammatory chemical of allergy

29
Q

function of basophils

A

Involved in many inflammatory reaction by
release histamine and other inflammation
factors
* contain heparin, an anticoagulant

30
Q

function of lymphocytes

A

two types: t cells and B cells
T cells: hunt down and destroy cells that are
infected with germs
* B cells: production of antibodies

31
Q

function of monocytes

A

Phagocytosis (eat) of microbes, foreign
particles, and dead cells

32
Q

what is the mechanism of blood clotting/ coaggulation

A
  1. Release of
    Thromboplastin(enzyme) (from
    platelet plug and other damaged
    cells)
    2.thromoplastin converts pro-thrombin (present in plasma) to thrombin
  2. thrombin concerts fibrinogen to fibrin (traps RBC, WBC, platelets)
33
Q

what are the main functions of blood

A

transport
-Gases (O2/CO2)
* Nutrients
Waste products
Hormones and enzymes
wbc
platelets

34
Q

example of lymph organs

A

spleen, thymus, tonsils , bone marrow

35
Q

what are the functions of the lymphatic system

A

To return excess tissue fluid to the circulating blood ( after filtering)
* To filter and trap damaged cells, microorganisms, foreign
substances, tumor cells by reticular fibers from the lymph before
returning to the bloodstreams
* To transport the products of fat digestion and the fat-soluble vitamins from the small intestine to the circulation
* The lymphatic system is sometimes considered as part of the
immune system, as it is where lymphocytes are activated

36
Q
  1. What are lymph nodes and what are their roles in the lymphatic system?
A

they are Bean shaped structure situated,
at intervals, along the lymph
vessels
their role store immune cells
and act as filters for the
lymphatic fluid that flows through
them.
* They trap bacteria, viruses, and
other foreign substances, which
are then destroyed by specialised
cells within the lymph node

37
Q
  1. What is the fluid that circulates within the lymphatic system and is responsible for carrying immune cells?
A

lymph

38
Q
  1. What is the largest lymph organ? What are its functions?
A

spleen, * Mainly acts as a filter for purifying
the blood, removing microbes by
phagocytosis
* Storage of blood (In horses, roughly
30% of the red blood cells are
stored)
* Destruction of worn out red blood
cells by phagocytosis
* Production of some lymphocytes

39
Q
  1. What is the location of the thymus and what is its function?
A

location: Located directly behind sternum
function: Site for the differentiation of T cells (T cells become mature in Thymus)

40
Q

main function of tonsil

A

First line defense against microbes
entering the mouth

41
Q

does the thymus last forever

A

The thymus begins to regress at the time of
adolescence and eventually completely disappears or
becomes a remnant