Topic 2 - Cells and Control Flashcards
what are chromosomes?
coiled up lengths of DNA molecules
what are cells called when they have two copies of each chromosome?
diploid
what are cells called when they have one copy of each chromosome?
haploid
when a cell divides by mitosis what is produced?
two cells identical to the original cell, the nucleus of each new cell contains the same number of chromosomes as the original cell
what is mitosis?
the stage of the cell cycle when the cell divides is mitosis, body cells in multi-cellular organisms divide to produce new cells during the cell cycle
why do multi-cellular organisms need mitosis?
growth, replacement of worn out cells, repair of damaged tissue, asexual reproduction
how do strawberry plants asexually reproduce by mitosis?
the strawberry plants form runners by mitosis which become new plants
what are the stages of mitosis in order and what is an acronym to remember them by?
IPMATC
Interphase, Prophase, Metaphase, Anaphase, Telophase, Cytokinesis
what is asexual reproduction?
when a single-celled organism can reproduce without the joining of male and female gametes.
what happens interphase in mitosis?
the DNA in the nucleus duplicates so that there is one copy of the DNA for each new cell
what happens in prophase in mitosis?
- the centriole doubles and moves to the poles of the cell - the centriole is represented in diagram as the letter ‘T’,
- the chromosomes condense and get shorter and thicker,
- the nuclear membrane breaks down so the chromosomes lie in the cytoplasm.
what happens in metaphase in mitosis?
the chromosomes line up on the equator of the cell and the centrioles attach spindle fibres to the centrometres of the chromosomes.
what happens in anaphase in mitosis?
the spindle fibres pull the chromosomes apart and reel in the chromatids (the different arms of the chromosome) to the centrioles (opposite ends of the cell)
what happens in telophase in mitosis?
nuclear membranes reform around each new set of chromosomes and these become the nuclei of the two new cells
what happens in cytokinesis in mitosis?
the cytoplasm and cell membrane divide to form two separate cells. these two cells are called daughter cells which are genetically identical diploid cells and which are genetically identical to the parent cell
how can you work out the number of cells there will be after multiple divisions of a cell by mitosis?
number of cells = 2^n , where n is the number of divisions by mitosis
what is growth?
growth is an increase in size or mass
what is cell differentiation?
the process by which a cell changes to become specialised for its function
how do plants grow?
by cell elongation
what is cell elongation?
when a cell elongates which results in growth e.g. a plant cell expands making the cell bigger and so making the plant grow
by what process does all growth in animals happen?
cell division
how does cell division result in growth in animals?
animals grow whilst they are young and then they reach full growth and stop growing, when animals are young cells divide at a fast rate but once an adult, cell division is mostly for repair - to replace old or damaged cells. so in most animals cell differentiation is lost at an early stage
growth in plants is mainly due to what process?
cell elongation
where is cell division used for growth in plant cells?
in the tips of the roots and shoots in meristems
how is plant growth different to animal growth?
plants often grow continuously so they continue to differentiate to develop new parts, but animals stop growing once adults so cell differentiation is lost at an early stage
what is the rate at which cells divide by mitosis controlled by?
chemical instructions - genes in an organism’s DNA
what is cancer?
an uncontrolled cell division
what is a tumour?
a mass of abnormal cells
when is a tumour considered cancerous?
when the tumour invades and destroys surrounding tissue
how does cancer start?
if there’s a mutation in one of the genes which controls cell division, the cell may begin dividing uncontrollably
what are percentile charts used for?
to monitor growth
why are growth charts used to assess a child’s growth over time?
so that an overall pattern in development can be seen and any problems such as obesity, malnutrition or dwarfism can be highlighted
what three measurements are taken of a baby to monitor its growth after birth to make sure that it is growing normally?
length, mass and head circumference
when are doctors likely to investigate a baby’s growth after using a percentile growth chart?
if the baby’s size is above the top percentile, below the bottom percentile, if the baby’s size increases or decreases by two or more percentile lines over time, or if there’s an inconsistent pattern (e.g. a small baby with a very large head.)
what are undifferentiated cells called?
stem cells
where are stem cells found?
in early human embryos and bone marrow.
how are embryonic stem cells different to adult stem cells?
- embryonic stem cells have the potential to divide and produce any type of cell because all of the different types of cells found in humans come from these stem cells,
- adult stem cells are only found in certain plaques such as bone marrow and can only produce certain types of cells because adult stem cells are used out replace damaged cells e.g. to make new skin or blood cells.
what are stem cells really important for?
the growth and development of organisms
what are meristems?
meristems contain plant stem cells and are the only cells which divide by mitosis in plant tissues
where are meristems found in plants?
in the areas of a plant that are growing, e.g. the tips of the roots and shoots
what are meristems used for in plants?
meristems produce unspecialised cells that are able to divide and form any cell type in plants - they act like embryonic stem cells but they can divide and differentiate to make any type of cell for as long as the plant lives. meristems are used to produce specialised tissues such as the xylem and phloem
how are adult stem cells already used to cure some diseases?
sickle cell anaemia can sometimes be cured with a bone marrow transplant because the stem cells produce new blood cells
give an example of how could it be possible to use stem cells to replace those damaged by disease or injury
new cardiac muscles could be transplanted into someone with heart disease
what are some of the potential risks with stem cells?
tumour development, disease transmission, rejection
who is tumour development a risk with stem cells?
stem cells divide very quickly and if scientists are unable to control he rate at which the transplanted cells divide inside a patient then a tumour may develop
how is disease transmission a risk with stem cells?
viruses live inside cells and if donor stem cells are infected with a virus and this isn’t notices then the virus could be passed on to the recipient and therefore make them more ill
how is rejection a risk with stem cells?
if the transplanted cells aren’t grown using the patient’s own stem cells then the patient’s body may recognise the cells as foreign and trigger an immune response to try to remove them, the patient could take drugs to suppress rejection but this makes them susceptible to diseases
what ethical issues does research using embryonic stem cells raise?
some people argue that human embryos shouldn’t be used for experiments because each one is a potential human life but others think that the aim of curing patients who are suffering should be more important than the potential life of the embryos
what does totipotent mean?
a cell can differentiate into any type of cell and eventually produce a whole organism (embryonic stem cells)
what does pluripotent mean?
cells can differentiate into any type of tissue but not whole organisms
what does multipotent mean?
cells can only form a few types of tissue, e.g. haematopoetic stem cells in bone marrow can form types of blood cells
what makes up the central nervous system (CNS)?
the brain and the spinal cord