Topic 1.3 Flashcards
What’s a nucleotide?
A monomer for DNA
What are the 3 parts of a nucleotide?
Phosphate, Pentose sugar, Nitrogen base
How does a nucleotide form?
Deoxyribose uses a condensation reaction which creates a phosphoester bond + water
What are the two nitrogen groups containing bases?
Purines and Pyramidines
What’s the difference between a purine and a pyramidine?
Purines have 2 carbon rings whereas Pyramidines have 1
What are the Purine bases?
Adenine and Guanine
What are the Pyramidine bases?
Thymine, Cytosine, Uracil
What is a DNA molecule composed of?
Pentose sugars, phosphate groups and 4 types of nitrogenous bases
How are DNA bases held together?
With Hydrogen bonds
What are the 4 bases of DNA
Adenine, Guanine, Thymine, Cytosine
What are the 4 bases of RNA?
Uracil, Thymine, Cytosine, Adenine
What is stage 1 of DNA replication?
Helicase enzymes separates the two DNA strands
Breaks hydrogen bonds between bases
What’s stage 2 of DNA replication?
*Two strands of DNA are catalyzed by DNA polymerase
*Uses the ‘parent’ strands as templates
* Reads the sequence of bases in triplet and adds complimentary bases to form new strands.
What’s Stage 3 of DNA replication?
*DNA polymerase reads parent strand
*Builds leading strand towards the replication fork
What’s Stage 4 of DNA replication?
Once the mRNA copies the whole gene it detaches and leaves the nucleus through the nuclear pores and moves to the ribosome
What’s Stage 1 of protein synthesis?
mRNA is attached at the start codon, in triplet