topic 10 (part 1) Flashcards
7list the stages of the cell cycle
- G1 phase
- S phase
- G2 phase
- M phase
the cell cycle consists of _____ and _____?
interphase and mitosis
what is G0 phase also known as?
quiescent phase
what occurs during G0 phase?
non-dividing cells enter this phase and rest
cells exit G1 and enter G0 in order to _____
differentiate
differentiated cells enter from G0 to G1 after the action of _____?
growth factors (mytogens)
what are 3 types of cells differentiated according to their cell division potential?
- post-mitotic cells
- cells that divide upon appropriate stimulation (signals)
- cells with high mitotic activity
what are post-mitotic cells?
terminally differentiated cells which have lost their ability to replicate (permanently arrested at G0)
what is an example of a post-mitotic cell?
neural cells, RBCs, cardiac muscle cells
what is an example of cells that divide upon appropriate stimulation (signals)
lymphocytes upon antigenic presentation
what is an example of cells with high mitotic activity?
germ cells, stem cells, epithelial cells
what occurs during G1 phase? how long does it last?
- preparation for DNA replication
- protein synthesis/organelle production
- 5-6 hrs
what occurs during S phase? how long does it last?
- DNA synthesis
- 10-12 hrs
what occurs during G2 phase? how long does it last?
- preparation for mitosis
- (same as G1)
- 4-6 hrs
what are the 2 types of cells?
- somatic (diploid cells)
- gametes (haploid)
what are homologous chromosomes?
chromosomes that carry the same genes at the same positions
what occurs during interphase?
- chromosomes are not condensed
G1 - each chromosomes consists of one chromatid (not yet replicated)
S - DNA is replicated
G2 - each duplicated chromosome has 2 sister chromatids
what is the difference between sister chromatids and homologous chromosomes?
sister chromatids - are genetically identical and used in cell division
homologous chromosomes - composed of two different chromosomes that are not genetically identical despite containing the same sets of genes