Topic 10-3

Question 1

variable genes with easily observable phenotypes whose inheritance can be studied

Answer 1

genetic markers

Question 2

molecular techniques now allow mapping using ________, looking at variations in the DNA itself

Answer 2

molecular markers

Question 3

throughout the genomes there are small sections of DNA called _______ that consist of ______

Answer 3

microsatellites, short tandem repeats (STRs)

Question 4

where are microsatellites found?

Answer 4

non-coding regions and likely have no fxn

Question 5

different individuals will have different numbers of _____ at a locus

Answer 5

repeats

Question 6

positions in the genome where individuals vary in a single ntd base

Answer 6

single nucleotide polymorphisms (SNPs)

Question 7

a specific set of genetic variations (SNPs, deletions, etc) observed on a single chr or part of a chr

Answer 7

haplotype

Question 8

SNPs w/in a haplotype are _________ and tend to be inherited together

Answer 8

physically linked

Question 9

nonrandom assoc. b/w genetic variants w/in a haplotype is called:

Answer 9

linkage disequilibrium

Question 10

what is the purpose of genome-wide assoc. studies?

Answer 10

in humans, used frequently to study the genes that cause diseases