Tooth Development Flashcards
Name the embryonic layers that all body tissues develop from (3)
- Ectoderm
- Mesoderm
- Endoderm
What arises from Ectoderm? (3)
- CNS
- Tooth enamel
- Skin
What arises from Mesoderm? (4)
- Connective tissue
- Blood vessels
- Reproductive system
- kidney/urinary system
What arises from Endoderm?
- Alimentary canal
2. Respiratory system
What do teeth develop from?
Teeth germs
What is the name of the 4th cell type?
Neural crest/ Ectomesenchyme
How does the 4th cell type form?
Forms between the ectoderm and the neural tube (neural crest)
How is the neural tube formed? (2)
- Neural crest tissue migrates into the developing face and jaw
- Neural plate folds and forms a neural groove and the neural groove folds and forms a neural tube
What arises from Ectomesenchyme? (5)
- Dentine
- Cementum
- Pulp
- PDL
- Jaw bones
How does Mandibulofacial Dystosis occur?
Failure of ectomesenchymal cells to migrate
List the stages in tooth development (5)
- Initiation
- Morphogenesis
- Cytodifferentiation
- Late Bell stage
- Root formation
What happens in the initiation phase? (4)
- PEB develops at approx 6wks IUL
- Appears as a thickening in epithelium of the embryonic mount (stomadeum)
- This results in the growth of dental lamina into the connective tissue
- The PEB grows into the jaw and divides into 2 parts
What 2 parts does the PEB divide into during the initiation phase?
- Vestibular lamina
- Which breaks down to form the buccal sulcus - Dental Lamina (approx 7wks)
- Develops enamel organ
- Has tooth germs
- Formation of dental lamina initiated by neural crest cells
What happens to the dental lamina formed?
The lamina grows and then apoptosis will separate the 2 epithelial tissues, forming the teeth
What happens in the Morphogenesis phase?
BUD STAGE (8-10wks):
- Dental lamina thickens into a ‘bud’ stage enamel organ
- Ectomesenchymal condensation forms the dental papilla
CAP STAGE (11wks):
- The enamel organ forms a ‘cap’ over the papilla
- EEE + IEE meet at the cervical loop
What is the cervical loop a reference for?
Formation of the root
What does the dental papilla form?
All the other tissues apart from enamel:
- Dentine
- Cementum
- PDL
- Pulp
Function of the dental follicle?
Sac that holds tissue together
Function of the enamel organ?
Epithelial tissue that forms enamel
What is Hypohyidrotic Ectodermal Dysplasia? (2)
- HED is a genetic skin disease resulting in missing teeth/irregular teeth shape
- Coronoid teeth may be formed
How does Severe Hypohidotic Ectodermal Dysplasia differ from the usual? (3)
- Changes not always associated with teeth
- Associated with the absence/reduction in number/size/shape of teeth
- Also affects hair nails formation
What happens in the Cytodifferentiaton phase? (3)
BELL STAGE (14wks):
1. Enamel organ bell stage at approx 14wks
2 More cell layers differentiate into a more defined tooth shape
3. Bell stage forms 4 different cell layers
What cell layers are formed during the Bell stage of Cytodifferentiation (4)
- Stratum Intermedium
- Stellate Reticulum
- IEE
- EEE
When does the permanent tooth germ form during Cytodifferentiation? (2)
- At approx 12wks appears as an extension on the lingual side of the dental lamina
- This is the dental lamina for the permanent successor
When does the 1st permanent molar form?
At roughly 16wks the 1s permanent molar forms as a backwards extension of the dental lamina