Tooth Development Flashcards

1
Q

Tooth Layers

A
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2
Q

Enamel

What does it do?

A

Covers anatomical crown

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3
Q

Enamel

What is it?

A

Epithelial product

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4
Q

Enamel

Makeup

A

96% inorganic

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5
Q

Enamel

Thickness

A

2mm thick maximum

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6
Q

Enamel

Appearance

A

Translucent

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7
Q

Enamel

Importance

A

Non-vital

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8
Q

Enamel

Characteristics

A

Hard (KHN 360-390) and brittle

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9
Q

Dentine

What is it?

A

Specialised connective tissue

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10
Q

Dentine

Characteristics

A

Hard (KHN 75), strong and resilient

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11
Q

Dentine

Makeup

A

~70% mineral and 20% organic (collagen)

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12
Q

Dentine

Contains

A

Dentinal tubules

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13
Q

Cementum

What is it?

What does it do?

Resistant to…

A

Mineralised (connective) tissue

Covers the roots of the tooth and provides support

Resorption

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14
Q

Interactions between:

Epithelium (ectoderm) gives rise to

Mesenchyme (ectomesenchyme) gives rise to

First signs of development

A

Enamel and the hyaline layer of the root

Dentine, pulp, cementum, periodontium (periodontal ligament and bone)

6 weeks

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15
Q

Stages of the tooth germ

A
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16
Q

Bud Stage

What happens?

A

Spherical/ovoid epithelial condensation

Cell proliferation

No histodifferentiation or morphogenesis

17
Q

Cap Stage

What happens?

A

Cap-shaped enamel organ

Poorly histodifferentiated

Little morphogenesis

18
Q

Late Cap Stage

What happens?

A

Some histodifferentiation. The inner and outer enamel epithelia

Some morphogenesis

19
Q

Bell Stage

A
20
Q

Early Bell Stage

Enamel Organ

Ectomesenchyme

A

Inner enamel epithelium (forms amelobasts (enamel)). Stratum intermedium, stellate reticulum and outer enamel epithelium

Dental papilla (forms odontoblasts (dentine) and pulp). Dental follicle (forms cementum, PDL and bone)

21
Q

Bell Stage

A
22
Q

Dentinogenesis

Cytodiffererntiation

A

Dental papilla cells form odontoblasts

23
Q

Dentinogenesis

Matrix formation

A

Odontoblasts -Produce predentine (collagen rich)

Retreat inwards

Have a long cell process which forms the dentinal tubule

24
Q

Dentinogenesis

Mineralisation

A

Predentine mineralizes forming dentine

25
Q

Crown Stage

A
26
Q

Amelogenesis

Ameloblasts

A

Formed from the inner enamel epithelium

27
Q

Amelogenesis

Ameloblast secretes

A

Enamel protein matrix

28
Q

Amelogenesis

Mineralisation

A

Virtually immediate. ~15% mineral, 65% water, 20% proteins. Rapid increase to 30% mineral (“immature” enamel)

29
Q

Amelogenesis

Gradual Maturation

A

Further mineralisation to ~96% - this requires the removal of most of the enamel proteins

30
Q

Crown Stage

A
31
Q

Crown Complete

A
32
Q

Root Formation

What is the root?

What are they derived from?

Signals for initiation

A

Dentine and cementum

Ectomesenchyme

An epithelial (root sheath) signal is required for initiation