Salivary Glands and Oral Mucosa

Question 1

Oral Mucosa

Consists of what?

Answer 1

Stratified squamous epithelium, lamina proporia and submucosa (dense and loose connective tissue respectively)

Epithelium keratinized in some areas

Question 2

Non-Keratinized Oral Mucosa

Answer 2

Question 3

Tongue

Intrinsic muscle bundles

Answer 3

Longitudinal, Transverse and Vertical

Question 4

Papillae

Filifofrm (FL)

Answer 4

Conical shape, no taste buds (unlike other 3)

Question 5

Taste Bud

What are they?

Answer 5

Multicellular chemoreceptive units

Question 6

What does saliva do?

Protection

Answer 6

Flushes away non-adherent bacteria, debris, sugar

Question 7

Saliva

How much per day?

Answer 7

600-1000ml a day

Question 8

Major glands

3 major pairs

Answer 8

Parotid glands, submandibular glands and sublingual glands

Question 9

Structure of Salivary glands

Stroma

Answer 9

Tough connective tissue capsule, with septa dividing gland into lobes/lobules.

Question 10

Merocrine Secretion

Occurs…

Answer 10

By exocytosis. When membranes of secretory vesicles fuse with cell membrane and discharge contents into extracellular space

Question 11

Classification of Exocrine Glands by Duct Morphology

Simple

Compound

Answer 11

Unbranched

Has a branching duct system

Question 12

Classification of Exocrine Glands by Arrangement of Secretory Cells

Tubuloacinar

Answer 12

Secretory tubules ending in secretory acini

Question 13

Salivary glands

Secretory elements

Answer 13

Either serous or mucous

Question 14

Serous and Mucous cells

Answer 14

Question 15

Cells of Serous Acini

Shape

Answer 15

Typically wedge shaped

Question 16

Cells of Mucous Acini

Found

Answer 16

In tubular element of tubulo-acinar glandular structure.

Question 17

Serous Demilune

What is it?

Answer 17

Serous cells appearing as a crescent shaped collection of cells at the end of the secretory unit. Thought to be an artifact

Question 18

Duct System of Major Salivary Glands

Acinus empties into

Answer 18

Intercalated duct consisting of cuboidal cells

Question 19

Intercalated Duct

Empties into

Cells of striated duct

Answer 19

Striated duct

Are columnar, and have their nucleus in a central position with prominent striations at the basal surfaces.

Question 20

Collecting ducts (excretory ducts)

Emptied into by…lobular

Lined by

Answer 20

Striated ducts - Interlobular

Lined by pseudostratified columnar epithelium with tall columnar cells and small basal cells

Question 21

Serous vs Mucous

Answer 21

Question 22

Submandibular Gland

Answer 22

Question 23

Minor Glands

Found where?

Absent

What ones?

Answer 23

Scatted throughout oral mucosa

Gingiva and anterior hard palate

Lingual, minor sublingual, labial, palatine and buccal glands

Question 24

Minor Glands

Answer 24

Question 25

Von Ebner's Glands

Answer 25

Question 26

**_Tongue_** Dorsal surface

Answer 26

Has keratinized stratified sqamous epithelium on the bottom with dense irregular lamina proporia tying the epithelium to the muscle

Question 27

**_Papillae_** Fungiform (FG)

Answer 27

Blunt

Question 28

**_Papillae_** Foliate

Answer 28

Slit-like on margin of tongue

Question 29

**_Papillae_** Circumvallate

Answer 29

Large, dome shaped. 6-12 in two lines forming a "v" about 2/3 back on the tongue. Cleft around them.

Question 30

**_What does saliva do?_** Buffering

Answer 30

Bicarbonnate protects teeth

Question 31

**_What does saliva do?_** Tooth integrity

Answer 31

High levels of calcium and phosphate for remineralization

Question 32

**_What does saliva do?_** Antimicrobial activity

Answer 32

Mucins provide a barrier - antibacterial enzymes.

Question 33

**_What does saliva do?_** Digestion

Answer 33

Fluid and mucin components aiding in formation and swallowing of food bolus.

Question 34

**_What does saliva do?_** Taste

Answer 34

Able to help solubilize food so it can go to taste receptors

Question 35

**_Saliva_** How much is water?

Answer 35

99% water

Question 36

**_Saliva_** Secretion types?

Answer 36

Constitutive secretion and one under nervous control

Question 37

**_Saliva_** Where does 90% come from?

Answer 37

Comes from 3 pairs of major salivary glands

Question 38

**_Major glands_** Location

Answer 38

Located outside of oral cavity and have extensive duct systems

Question 39

**_Major glands_** Minor glands

Answer 39

Lots in oral mucosa. Typically located in submucosa and have short ducts that open onto the mucosal surface

Question 40

**_Structure of Salivary glands_** Parenchyma

Answer 40

Compound tubulo-acinar glands. Serous acini, mucous acini and mixed acini - type present depends on gland. Secretion is merocrine.

Question 41

**_Salivary glands_** Serous cells

Answer 41

Thin, watery secretion containing proteins (like amylase) and ions. Not ultrafiltrate of blood but produced via active secretion.

Question 42

**_Salivary glands_** Mucous cells

Answer 42

Produce mucin. Consists of a protein core highly decorated with sugar residues resulting in a viscous, sticky secretion.

Question 43

**_Cells of Serous Acini_** Nucleus

Answer 43

Prominent and in basal part of cell

Question 44

**_Cells of Serous Acini_** RER

Answer 44

Extensive RER

Question 45

**_Cells of Serous Acini_** Appearance

Answer 45

Granular appearance due to large numbers of apical secretory granules

Question 46

**_Cells of Mucous Acini_** Granules

Answer 46

Large numbers of prominent mucin granules packing the cytoplasm

Question 47

**_Cells of Mucous Acini_** Nucleus

Answer 47

Compressed towards basal part of cell