Tobacco, Vaping, Medical Marijuana, and Cannabidiol Flashcards
What is the main factor contributing to juul/vaping being “safer” than cigarette smoking
Cigarette smoke contains thousands of chemicals including over 70 carcinogens
e-cigs have about 80 total chemicals
Why is the use of e-cigarettes so conerning
Children use them because they taste better than real tobacco.
What happens during the course of a child becoming addicted to nicotine
harms developing brain
leads them to burned tobacco products
former smokers become re-addicted
how does nicotine damage a developing brain
- damages prefrontal cortex
- decreased memory and attention
- impairs neuroplasticity
What was the main suspected culprit in the outbreak of lung disease from vaping?
Vitamin E acetate
describe the endocannabinoid system
- produced by post synaptic neuron
- retroactively travel to presynaptic neuron
- -anandamide and 2 AG
- -hyperpolarize presynaptic neuron
what is the indication for Dronabinol
synthetic THC used for
- analgesia
- appetite
- muscle relaxation
Via CB1 receptors
What is the pill form of THC used for chemo induced nausea and vomiting
Nabilone
What are the adverse effects of THC
Affects judgement and coordination Sedation, injected eyes, depression, dizziness, tachycardia, hypotension but also can damage developing brains "gateway drug"
What conditions is cannabis NOT effective
Acute pain Tremor in MS HD Glaucoma Schizophrenia Depression
What are contraindications in the use of cannabis
- history of psychosis
- current or past substance abuse
- cardiovascular or respiratory diseasE
Why are Fatty Acid Amide Hydrolase (FAAH) inhibitors a hot topic
they block breakdown of the endocannabinoids which can lead to analgesia. None have been successful so far.
How well is CBD absorbed orally?
It isn’t, better to do sublingually.
Is CBD safe?
Sure as fuck seems to be
What are the two seizure disorders that Epidiolex is approved for
Dravet Syndrome
Lennox-Gastaut
