Thyroid & Parathyroid Agents

Question 1

Thyroid Hormones

Answer 1

Drug - Levothyroxine, Liothyronine, Liotrix, Thyroid Desiccated
Action - increases cellular metabolism Hypothyroidism
Relative - Acute MI, thyrotoxicosis
Caution - hypoadrenal Conditions
AE - skin reaction, S Hyperthyroidism, cardiac stimulation, cns affects
Drug 2 Drug - Oral Anticoagulants, Digoxin, Theophylline

Question 2

Antithyroid Agents - Thiomides

Answer 2

Drugs - Propylthiouracil (PTU), Methimazole -kids
Action - prevents the formation of TH, hyperthyroidism
Caution- liver impairment
AE - hypothyroidism, liver toxcity, bone marrow suppression
Drug to Drug - oral Anticoagulants, Theophylline, beta-blockers, digoxin

Question 3

Antithyroid Agents - Iodine Solutions

Answer 3

Drugs - Strong Iodine Solution, Potassium Iodine, Sodium Iodine i113 & i123
Action - Prevent TH from forming, # drugs destroy thyroid with radiation
Caution- liver impairment
AE - hypothyroidism, Iodine
Drug 2 Drug - oral Anticoagulants, Theophylline, Beta-Blockers, Digoxin

Question 4

Anti-Hypocalcemic Agents

Answer 4

Drugs - Teriparatide, Parathyroid Hormone, Calcitriol (vit D)
Action - Stimulats ostioclasts to release Calcium, Hypocalcemia, hypoparathyroidism, treat Osteoprosis

Question 5

Anti-Hypercalcemic Agents