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CLINICAL CHEMISTRY > THYROID DISORDER > Flashcards

THYROID DISORDER Flashcards

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1
Q

thyroid antibody involved in tissue destruction process

A

thyroperoxidase autoantibody

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2
Q

thyroid antibody involved in hashimoto’s disease

A

thyroperoxidase autoantibody

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3
Q

thyroid antibody involved in grave’s disease

A

TSH receptor autoantibody

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4
Q

thyroid antibody classifies as stimulating or blocking antibody

A

TSH receptor autoantibody

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5
Q

it refers to an excess of circulating thyroid hormone

A

hyperthyroidism

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6
Q

primary hyperthyroidism lab result

A

T3 and T4 is increased
TSH is decreased

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7
Q

secondary hyperthyroidism lab result

A

FT4 and TSH is increased

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8
Q

is applied to a group of syndromes caused by high levels of free thyroid hormones in the circulation

A

thyrotoxicosis

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9
Q

T3 thyrotoxicosis is also known as

A

plummer’s disease

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10
Q

T3 thyrotoxicosis or plummer’s disease lab result

A

FT3 is increased
FT4 is normal
TSH is low

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11
Q

T4 thyrotoxicosis lab result

A

T3 is normal or low
T4 is increased
TSH low

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12
Q

it is the most common cause of thyrotoxicosis

A

grave’s disease

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13
Q

grave’s disease is also known as

A

diffuse toxic goiter

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14
Q

it is an autoimmune disease in which antibodies that activates the TSH receptor

A

grave’s disease

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15
Q

how many times grave’s disease occurence on women than men

A

6x

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16
Q

features of hyperthyroidism

A

exophthalmos (bulging eyes)
pritibial myxedema

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17
Q

diagnostic test for grave’s disease

A

TSH receptor antibody test

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18
Q

a disorder where the thyroid turns into a woody or stony-hard mass

A

riedel’s thyroiditis

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19
Q

in riedel’s thyroiditis the thyroid turns into

A

woody or stony-hard mass

20
Q

a disorder where there is no clinical symptoms but TSH is low, and FT3 and FT4 is normal

A

subclinical hyperthyroidism

21
Q

it is associated with neck pain, TPO negative, and ESR and thyroglobulin is elevated

A

subacute granulomatous (painful thyroiditis)

22
Q

subclinical hyperthyroidism lab result

A

TSH is low
FT3 and FT4 is normal

23
Q

subacute granulomatous (painful thyroiditis) lab result

A

TPO negative
ESR and thyroglobulin is elevatedq

24
Q

it develops whenever there is insufficient amounts of thyroid hormone are available to tissues

A

hypothyroidism

25
Q

hypothyroidism treatment is

A

levothyroxine

26
Q

hyperthyroidism signs and symptoms

A

tachycardia
weight loss
heat intolerance
menstrual changes

27
Q

hypothyroidism signs and symptoms

A

bradycardia
weight gain
cold intolerance
mental dullness

28
Q

it is primary due to deficiency of elemental iodine

A

primary hypothyroidism

29
Q

primary hypothyroidism lab result

A

T3, T4, and TSH is low

30
Q

primary hypothyroidism may be caused by drugs like

A

lithium

31
Q

it is the common cause of primary hypothyroidism

A

hashimoto’s disease

32
Q

it is characterized by sensitized T-cell autoantibody binds to the cell membrane causing cell lysis and inflammatory reaction

A

hashimoto’s disease

33
Q

in primary hypothyroidism the thyroid gland is

A

enlarged

34
Q

primary hypothyroidism lab result

A

T3 and T4 is decreased

35
Q

describes as the peculiar nonpitting swelling of the skin

A

myxedema

36
Q

severe form of primary hypothyroidism

A

myxedema coma

37
Q

it is due to pituitary destruction of pituitary adenoma

A

secondary hypothyroidism

38
Q

secondary hypothyroidism lab result

A

T3, T4, and TSH is decreased

39
Q

tertiary hypothyroidism lab result

A

T3, T4, and TSH is decreased

40
Q

it is a defect in the development or function of the gland

A

congenital hypothyroidism/cretinism

41
Q

congenital hypothyroidism/cretinism symptoms

A

physically and mentally retarded

42
Q

congenital hypothyroidism/cretinism screening test

A

T4 (decreased)

43
Q

congenital hypothyroidism/cretinism confirmatory test

A

TSH (increased)

44
Q

TSH value interpretation

A

TSH;

<10 mIU/L (no further test)
10-20 mIU/L (repeat test in 2-6 weeks)
>20mIU/L (for endocrinologic evaluation to diagnose hypothyroidism)

45
Q

subclinical hypothyroidism lab result

A

T3 and t4 is normal
TSH is slightly increased

CLINICAL CHEMISTRY (6 decks)

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