ENDOCRINOLOGY Flashcards
growth hormone is also known as
Somatotropin
growth hormones Major Stimulus
DeepSleep
Hypoglycemia
growth hormones Major inhibitor
Stomatostatin
It is due to over production of GH (somatotropin)
acromegaly
Acromegaly: Clinical Feature
Prognathism
Acromegaly: Causes
Iatrogenic
Ectopic
Pituitary tumor
wermer’s syndrome
Acromegaly: Signs and Symptoms
Skin thickening
Hyperhidrosis
Protrusion of the mandible
elongation of the facial bone
Screening test for acromegaly
Somatomedin C
Insulin-like Growth Factor 1 (IGF-1) Test
Confirmatory Test for acromegaly
Glucose Suppression Test - Oral Glucose Tolerance Test (OGTT)
growth hormone reference range
<1 ng/mL
it is caused by a lack of antidiuretic hormone
(ADH),
diabetes insipidus
antidiuretic hormone
(ADH) is also known as
vasopressin
Four types of diabetes insipidus
cranial,
nephrogenic
gestational
dipsogenic
characterized by excessive release of the enzyme vasopressin by the placenta
Gestational Diabetes Insipidus
serum osmolality of diabetes insipidus
increased
urine osmolality of diabetes insipidus
decreased
normal level of osmolality
275-295 mOsm/kg
it measures the serum
and urine osmolality
Water Deprivation Test (Gold Standard) -
differential test for diabetes insipidus
Desmopressin Test
is a disorder that occurs when
your body makes too much of the hormone cortisol
over a long period of time.
cushing’s syndrome
It is a hormone produced by the pituitary gland
in the brain. The primary function of ACTH is to
stimulate the production and release of cortisol
from the adrenal glands.
andrenocorticotropic hormone (ACTH)
manifestation of patient with cushing’s syndrome
Striae rubrae Hematoma Muscle weakness
Obesity Buffalo hump Moon face
Hirsutism / Acne
is a rare endocrine disease in
which there is destruction of the adrenal cortex
caused by autoimmune adrenalitis, tuberculosis,
hemorrhage, or HIV infection, with resultant
inadequate secretion of the adrenal cortical
hormones-cortisol, aldosterone and androgens
addison’s disease
it is the Principal Glucocorticoid
cortisol
cortisol reference range
5-25 ug/dl
level of cortisol and aldosterone during primary adrenal insufficiency
primary hypocortisolism
treatment for addison’s disease
Prednisone
Hydrocortisone