thyroid antibody Flashcards
Describe the relationship between anti-TPO antibodies and Graves’ disease.
Anti-TPO antibodies are present in 70-80% of patients with Graves’ disease.
What is the percentage of patients with autoimmune hypothyroidism who have anti-TPO antibodies?
95% of patients with autoimmune hypothyroidism have anti-TPO antibodies.
Define TRAb.
TRAb stands for Thyroid Receptor Antibodies.
What is the role of TRAb in Graves’ disease?
TRAb in Graves’ disease can be stimulating, causing overactivity of the thyroid gland.
Describe the relationship between anti-Tg antibodies and autoimmune hypothyroidism.
Anti-Tg antibodies are present in 60% of patients with autoimmune hypothyroidism.
What is the percentage of patients with Graves’ disease who have TRAb antibodies?
70-100% of patients with Graves’ disease have TRAb antibodies.
How do heterophile antibodies in patient sera affect thyroid function test results?
Heterophile antibodies can cause abnormal interference, leading to abnormally low or high values of FT4 and FT3.
What can be used to remove heterophile antibodies from patient sera?
Absorption tubes can be used to remove heterophile antibodies from patient sera.
Do TRAbs in autoimmune hypothyroidism have a stimulating or inhibitory effect?
TRAbs in autoimmune hypothyroidism have a blocking or inhibitory effect.
